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A study published by the Center for Physiology and Muscle Biology in the journal FASEB found that resistance exercises regulate fat cell metabolism at the molecular level
.
The results of studies in mice and humans show that under mechanical load, muscle cells release particles called extracellular vesicles, which instruct fat cells to enter fat burning mode
.
Extracellular vesicles were originally thought to be a way for cells to selectively eliminate proteins, lipids and RNA
.
Recently, scientists discovered that they also play a role in cell-to-cell communication
The author of the study, Dr.
John McCarthy, an associate professor in the Department of Physiology in the United Kingdom, said that this study adds a new dimension to how skeletal muscle communicates with other tissues through extracellular vesicles
.
McCarthy said: "As far as we know, this is the first demonstration of how weight training initiates metabolic adaptation in adipose tissue, which is critical to determining the outcome of systemic metabolism
.
" "Resistance exercise-induced extracellular vesicles improve fat metabolism.
McCarthy’s research team was led by postdoc Ivan Weitch, now at the University of Nebraska, in collaboration with the Muscle Biology Center, and led by Joseph Hamburg-sponsored professor Dr.
The research reported in this publication was supported by the National Institute of Diabetes, Digestive and Kidney Diseases of the National Institutes of Health, and the award number is R01DK119619
Journal Reference :
Ivan J.
