How many asymptomatic infections are there? How far are we from "mass immunization"?

According to the World Health Organization, the cumulative number of people diagnosed with the new coronavirus worldwide has exceeded 11 million so farHowever, this figure is confirmed by the number of patients tested for nucleic acidWe know that about 80 percent of patients infected with the new coronavirus have mild or no symptoms, and many of them may never have been tested for nucleic acids or know if they have ever been infected with the new coronavirusSerological testing, which can detect the presence of antibodies against the new coronavirus in the patient, to better understand the number of people who have been infected with the new coronavirus, is important in epidemiological research and public health managementIn a paper published in the Lancet,,sista lying in more than 60,000 participants nationwide in SpainThe study found that about one-third of serotonin-positive participants did not exhibit symptoms associated with COVID-19Nationwide, only 5 per cent of participants tested positive for serotonin, and in urban areas such as Madrid, where the new crown outbreak is severe, the serotonin rate was no more than 15 per centIn their paper, the researchers said the data showed that the Spanish population was still far from meeting the criteria for herd immunitytesting methods
the Serological Epidemiological Survey called ENE-COVID, is a serological study covering the entire population of Spain to investigate the serotonin positive proportion of the new coronavirus in the Spanish populationThe study randomly selected 35,883 families based on population data and invited these family members to participate in serological tests, which eventually added to the studyparticipantsresearchers tested participants using two different serological tests, one that was 100 percent specific to IgG antibodies to the new coronavirus and 82.1 percent sensitivity, while the other, a chemical fluorescent response-based immunotest (called "immune testing") with a specificity of 100 percent and a sensitivity of 89.7 percentA total of 51,958 people received both instant and immunoassaysresultsserological tests showed that between 27 April and 11 May 2020, the population-wide population in Spain had a 5.0% senocmarkoured rate (using instant testing) and used immunotests, a figure of 4.6 per cent, 3.7 per cent of participants tested positive in both tests and 6.2 per cent of participants tested positive in one of them In the seven provinces with the worst outbreaks in central Spain, the serotonin positive rate is between 10 and 15 per cent study found no significant difference in serotonin positive rates between men and women, but instant testing showed that the seropositive rate was 1.1% in infants under one year of age and 3.1% in children aged 5-9 The proportion of serotonin-positive participants who did not report new coronary symptoms was 32.7% (immediate testing) or 28.5% (immune testing) About 90% of patients with COVID-19 who were diagnosed with positive nucleic acid tests 14 days before receiving serotonin tests were serotically positive some of the revelations
The Lancet published a commentary today on the significance of the study In addition to the Spanish study, a serological survey of the population of Switzerland and Wuhan, China, yielded similar results, the commentary noted A key finding of these serological surveys is that the majority of the population is still not infected with the new coronavirus, even in areas where the outbreak is so severe that it is putting a heavy strain on the health system This means that at the population level, we are still far from reaching the level of mass immunization researchers conducting spanish serological surveys, who discussed the paper, noted that about one-third of people infected with the virus with neo-coronary virus were asymptomatic The findings further underscore the importance of rapid detection, research and isolation of people diagnosed with newly coronavirus infectionand and those who have come into contact with them (
Biovalley Bioon.com)