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Pharmacovigilance actually has a special term called pharmacovigilance
Pharmacovigilance can detect risks earlier
Pharmacovigilance can detect risks earlierFor example, the drug rofecoxib was found to have serious cardiovascular adverse reactions after 5 years of listing, and it was eventually withdrawn from the market.
Sentinel Program for Drug Surveillance in the United States
Sentinel Program for Drug Surveillance in the United StatesIn 2008, the US FDA launched the Sentinel Program
The US FDA's sentinel mode can monitor the risk of drugs throughout the entire life cycle of drugs, automatically classify their risk levels, and automatically identify safety issues
It is extremely difficult to determine the relationship between adverse events and drugs
It is extremely difficult to determine the relationship between adverse events and drugsA variety of adverse events will occur in clinical practice, including vomiting, diarrhea, fever and palpitations
summary
summaryThe focus of pharmacovigilance is on active discovery, which is based on high-level data mining and automated analysis systems
Combining multiple data sources for pharmacovigilance has great research potential