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    Home > Active Ingredient News > Endocrine System > How is acute hypocalcemia treated? The director prefers this drug!

    How is acute hypocalcemia treated? The director prefers this drug!

    • Last Update: 2022-11-05
    • Source: Internet
    • Author: User
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    Diagnose and treat big and small issues, and see what the guidelines say


     


    Severe acute/symptomatic hypocalcemia, what is the preferred treatment? Usually preferred: intravenous drip of calcium gluconate (due to its high safety, extravasation rarely causes tissue necrosis).


    Initial rapid instillation:
    • Add 1 g or 2 g of calcium gluconate (equivalent to 90 mg or 180 mg of elemental calcium) to 50 mL of 5% glucose solution or normal saline for intravenous infusion for 10-20 min
      .
    • Infusions should not be given too quickly, as this may lead to severe cardiac insufficiency, including systolic arrest
      .
    • This dose of calcium gluconate can only maintain the serum calcium concentration for 2 to 3 hours, and patients with persistent hypocalcemia also need to continue slow calcium infusion
      .

    slow calcium infusion:
    • The infusion was prepared with 10% calcium gluconate (90 mg/10 mL elemental calcium) or 10% calcium chloride (270 mg/10 mL elemental calcium).

      Add 11g of calcium gluconate
      (1000mg of elemental calcium) to normal saline or 5% glucose solution to prepare a 1000mL solution, that is, an intravenous infusion containing 1mg/mL of elemental calcium
      is obtained.
    • Initially infusion at a rate of 50 mL/hour (equivalent to 50 mg/h elemental calcium).

      Then the dose can be adjusted appropriately to maintain
      the blood calcium at the lower limit of the normal range, and patients usually need 0.
      5-1.
      5mg/(kg·h) of elemental
      calcium (using the serum calcium value after correcting serum albumin abnormalities).


     Extended question: For severe acute hypocalcemia, what is the preferred oral treatment?

    What are the diagnostic criteria for major diseases?

    What are the preferred therapeutic agents and regimens?

    What clinical signs and symptoms are the priority to focus on in diagnosing a disease?


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