Hops extract reduces the risk of breast cancer

Hops plant flower head can be used for brewing beer flavor and maintaining beer stability, and can also be used as a dietary supplement to treat menopausal symptoms and other diseases Hormone replacement therapy is known to increase the risk of breast cancer, so some women use hops extract as an alternative therapy, but the effect of hops extract on cancer is not clear A new study from the University of Illinois (UIC) research center in Chicago has shown a link between hops extract and reduced breast cancer risk Long term exposure to estrogen has long been considered a risk factor for breast cancer, especially in menopausal women To relieve hot flashes and other menopausal symptoms, some women use hormone replacement therapy (HRT) to replace the missing hormones, including estrogen However, HRT is known to be associated with an increased risk of breast cancer and heart disease, so some women are looking for other natural alternatives, such as hops extract, which contains phytoestrogens or phytoestrogens However, the effect of hops extract on cancer risk is not clear The researchers pointed out that preliminary laboratory studies showed that some of the active substances in hops may have protective effects, so they decided to conduct further research The researchers tested the effect of hops extract and 6-pn on estrogen metabolism, which is related to the occurrence of breast cancer The researchers tested two different breast cell lines The results showed that one of the hops, especially 6-pronylnaringenin (6-pn), could enhance the detoxification pathway of cells Previous studies have shown that this pathway is associated with a reduced risk of breast cancer "The results show that hops extract and 6-pn can preferentially induce 2-hydroxylation pathway of two cell lines," the authors pointed out Finally, they concluded that the findings suggest that 6-pn may be anticancer, but further studies are needed to confirm it The incidence rate of breast cancer is only behind skin cancer among American women, but some men can also develop breast cancer It is estimated that in 2012, about 224147 women and 2125 men in the United States were diagnosed with breast cancer, and eventually 41150 women and 405 men died of the disease.