High protein diet can improve blood glucose control in diabetic patients

A new study, published at this year's EASD annual meeting, shows that a high protein diet improves blood sugar control in patients with type 2 diabetes and has no adverse effects on renal function This study was carried out by Mariya Markova of the German Institute of human nutrition (DIFE), charit é Medical College, Berlin, Germany, and his colleagues Previous studies have reported that high protein diet has a beneficial effect on type 2 diabetes, but also reported that it has adverse effects The new study compared the effects of two high protein diets with the same calories - animal protein (AP) and plant protein (PP) - on metabolic function and liver fat content A total of 37 patients (24 men and 13 women) with type 2 diabetes mellitus (average age 65 years old, average body mass index 30 kg / M?, average glycosylated hemoglobin 7.0%) were randomly assigned to a high animal (meat and dairy products) or high plant (food pulse) protein diet (30% protein, 30% carbohydrate, 40% fat) for 6 weeks Before and after dietary intervention, the above parameters were measured The researchers found that after the intervention, the liver enzyme test results were improved in both groups, and the liver fat and glycosylated hemoglobin were reduced in all patients Only the insulin sensitivity of AP group was improved, while the serum creatinine of PP group was significantly reduced (suggesting better renal function), and the overall renal function was improved (calculated by glomerular filtration rate) AP group did not have the above findings "In diabetic subjects, a high protein diet for six weeks improved glucose metabolism and reduced liver fat content, an effect unrelated to animal or plant-derived proteins," the authors concluded The high protein diet had no adverse effect on the kidney, and the renal function of the subjects with the plant proteome was actually improved " Long term observational studies in larger populations are needed to confirm their findings, the authors say At present, they are observing the expression of key genes involved in fat metabolism, sugar metabolism and inflammation in blood cells and fat cells to determine whether there is food induced change, so as to understand the impact of high amino acid intake on the molecular level.