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A recent study reported that the platelet-to-leukocyte ratio (PWR) was an independent prognostic predictor of acute promyelocytic leukemia
A recent study reported that the platelet-to-leukocyte ratio (PWR) was an independent prognostic predictor of acute promyelocytic leukemia
The researchers recorded clinical information at the time of disease diagnosis and calculated the ratio of platelet count to white blood cell count in 338 CN-AML patients
To assess the prognostic value of PWR, we divided patients into low, intermediate, and high based on three equal quartiles of PWR values (Q1: <33.
Figure 1.
Figure 1.
Figure 2.
Figure 2.
Figure 3.
Figure 3.
The findings suggest that higher PWRs have higher levels of platelet counts and lower levels of white blood cell counts, percentage of bone marrow blasts, FLT3-ITD and NPM1 mutations
FLT3 NPM1, DNMT3A IDH1 IDH2 ASXL1 TET2
Overall, this study found that the platelet to white blood cell count (PWR) ratio could be used as an independent predictor of overall survival and event-free survival in CN-AML patients
Original source:
Original source:Zhao S, Pan H, Guo Q, Xie W, Wang J.
Zhao S, Pan H, Guo Q, Xie W, Wang J.
Platelet to white blood cell ratio was an independent prognostic predictor in acute myeloid leukemia.
Hematology.
2022 Dec;27(1):426-430.
doi: 10.
1080/16078454.
2022 .
2055857.
PMID: 35413229.
Zhao S, Pan H, Guo Q, Xie W, Wang J.
Platelet to white blood cell ratio was an independent prognostic predictor in acute myeloid leukemia.
Hematology.
2022 Dec;27(1):426- 430.
doi: 10.
1080/16078454.
2022.
2055857.
PMID: 35413229.
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