Heavyweight discovery! You should be fat if you don't eat breakfast!

Irregular eating habits, such as not eating breakfast, are often directly related to a variety of diseases, such as obesity, type 2 diabetes, high blood pressure and cardiovascular disease, but researchers are not clear about the specific impact of eating time on the body's biological clock Recently, in a research report published in the international journal Diabetes Care, researchers from Tel Aviv University clarified the effect of breakfast on the expression of "clock genes", which can regulate the glucose level of healthy individuals and diabetic patients after meals, namely insulin response This year's Nobel Prize in physiology or medicine was awarded for the study of the importance of the body's biological clock and the effect of meal time on the body's health The researchers elucidated the molecular mechanism controlling the body's circadian clock According to Professor Daniela Jakubowicz, our study shows that breakfast can induce the expression of clock gene in the inherent cycle of the body, thus improving the blood sugar control of the body The clock gene of circadian rhythm (biological clock gene) can not only regulate the circadian rhythm change of glucose metabolism, but also regulate the body weight, blood pressure, endothelial function and atherosclerosis Proper meal time, such as breakfast before 9:30 in the morning, can effectively improve the overall metabolism of the body, promote weight loss, and slow down the complications of type 2 diabetes and other age-related diseases In the study, the researchers recruited 18 healthy volunteers and 18 diabetics Obese volunteers were asked to take part in a breakfast and lunch themed test, as well as a lunch only test Then, the researchers tested participants' blood pressure to determine the clock gene expression, blood glucose level, insulin, and complete glucagon like peptide in their bodies after eating -1 (iglp-1) and dipeptidyl peptidase IV (DPP-IV) plasma activity According to the researchers, we found that eating breakfast can stimulate the expression of appropriate clock genes in the body to improve blood glucose control In all study groups, eating breakfast can actually improve the expression of special clock genes in the body of participants, and these are genes that can effectively promote body weight loss, which can improve the level of glucose and insulin in the body after lunch For lunch only participants (no breakfast), the expression of clock genes related to weight loss will be down regulated, resulting in high blood sugar and poor insulin response in the body, which indicates that not eating breakfast or inducing weight gain, even if there is not too much food in the rest of the day Finally, researcher Jakubowicz said that in fact, we can change the gene expression of the body in only four hours, which may be very impressive At present, we are carrying out a long-term study to compare the effects of different meal times on the clock gene expression, glucose balance and weight loss of the body.