Heavy! Chinese scientists discover the only species of african swine fever

Recently, the Institute of Military Veterinary Medicine, Shandong Lansi Seed Industry Co., Ltd., Beijing Institute of Livestock and Veterinary Medicine and Harbin Veterinary Research Institute, four research institutions jointly published in the Chinese Journal of Veterinary Medicine, "China's Lansewhite No 2 pig anti-African swine plague characteristics identification" research paper, the text proved through experiments, Lansing White 2 pigs and artificial infection of the African swine plague virus has a clear resistance RZvRZv The article said that for African swine fever (ASF), some domestic pigs have resistance phenomenon, in Africa, wild boars, warthogs, jungle pigs, etc can be infected, but not ill In recent years, disease-resistant breeding is one of the important directions of breeding, which can improve the general and special resistance of individuals There are more research reports on disease-resistant breeding in pigs, and the more successful blue ear disease resistant pigs obtained by gene editing RZv experimental process and results
RZv The experiment selected 6 pigs of 10 weeks aged Lansing White 2 and ordinary white pig respectively, and used ASFV SY18 strains for oral attack after 21 days of regular feeding in P3 laboratory.　It was found that the average white pig died within 10 days, while the blue white 2 pig all but one died, all five of them were healthy Moreover, the blue white 2 pig developed viral emias later than the average white pig RZv ordinary domestic pigs in the drug attack 3 to 9 days after the appearance of fever, anorexia, depression, hilybes, etc , and eventually died, while Blue Si Bai 2 pig after the attack only mild fever, continued to return to normal after different times, clinical performance is normal, no anorexia, depression, hilyandre and other symptoms RZv, the researchers also found that the L.A White 2 pig began producing antibodies 2 weeks after contracting African swine fever, while the average domestic pig died before it was produced This shows that the inherent immune response of Blue White 2 pigs to african swine fever virus is significantly different from that of ordinary domestic pigs, judging from the relevant indicators, its resistance to the African swine plague virus may be stronger than that of African wild boars RZv showed good ASF resistance in production
RZv during the ASF epidemic, not only the whole group survived, but also after being a "sentry pig", and then after being reared with the epidemic-affected ordinary domestic pigs did not become ill, showing good ASF resistance some farmers have used these pigs to be rebred in empty-bar pig houses affected by the outbreak (African swine plague virus nucleic acid test positive farm), and have successfully re-raised more than 2,700 fat pigs and parents to breed pigs RZv In addition, in addition to this test in the P3 laboratory, the breeding enterprises will also be Blue SiBai 2 pig as a sentinel pig and affected by the outbreak of ordinary domestic pigs mixed, sentinel pig for a continuous period of 1 year of observation, the results of the sentinel pig has not shown the clinical symptoms of African swine fever during the observation period RZv Although antibodies to the African swine fever virus in the Lance White 2 pig serum were still positive at the end of the observation period (28 days after the attack), the virus nucleic acid was negative in the actual production of sentinel pigs The results suggest that long enough to completely remove the virus from the body RZv Blue Speight 2 pig is also resistant to other infectious diseases
RZv it is learned that Shandong Lansing Seed Industry Co., Ltd in 1999 from the United Kingdom to introduce about the Xia species of pigs, the use of 23 male pig family and 71 sow family, after nearly 20 years of hybrid breeding, to obtain Blue SiBai 2 pig Blue White 2 pig is not obtained through gm technology, but after nearly 20 years of breeding, through the comprehensive clinical phenotype to choose, long-term breeding gradually obtained anti-stress, disease resistance, good production and other phenotypes optimization and improvement, in the actual breeding process, in the case of non-immune vaccine, rarely occur other infectious diseases RZv researchers predict that the Lance white 2 pig not only has resistance to African swine fever, may also have the ability to resist many other infectious diseases, and, from the point of view of disease resistance, because of the long period of disease resistance, the disease resistance of blue white 2 pigs is strong, multi-potential, but these potential capabilities need to be verified by more testing RZv The disease-resistant characteristics of the pigs should be hereditary, but the genetic pattern of this disease-resistant trait is not clear As far as researchers know, Blue SiBai Bai 2 pig is the only African swine plague resistance great white pig breed in the world, it is urgent to protect species, expand the promotion and in-depth study the discovery of Blue Spall 2 pig and the verification of anti-African swine fever characteristics have brought a dawn for China to guarantee the supply of pigs without the African swine fever vaccine, and have also brought new hope for the elimination or elimination of Swine fever in China and the world as a whole of the
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