The secret to healthier skin and joints may lie in gut microbes
Sam T.
Psoriasis is a stubborn skin disease related to the human immune system
Food is one of the main variable factors that regulate the intestinal microbiota
Because the bacteria in the intestine may play a key role in the formation of inflammation, the researchers tried to test whether the intestinal dysbiosis would affect the skin and joint inflammation
Researchers have found that a short-term Western-style diet seems to be sufficient to cause an imbalance of the human intestinal microbes and increase sensitivity to IL-23-mediated psoriasis-like skin inflammation
Hwang said: “There is a clear link between skin inflammation and changes in the gut microbiota caused by food intake
After feeding the mice on a Western-style diet for 6 weeks, the researchers randomly divided the mice into two groups: one group continued on the Western-style diet for 4 weeks, and the other group switched to a balanced diet at the same time
Zhenrui Shi, the first author of the study and a visiting assistant researcher in dermatology at the University of California, Davis, said: "It is surprising that a simple dietary adjustment with less sugar and less fat may have a significant effect on psoriasis
Related paper information: https://doi.
https://doi.
org/10.
1016/j.
jid.
2020.
11.
032
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