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HCQ may have slight benefit for proteinuria in patients with IgA nephropathy

 Last Update: 2022-08-16
 Source: Internet
 Author: User

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IgA nephropathy, also known as Berger's disease, is the most common primary glomerulonephritis and chronic glomerular disease in the wor.

Proteinuria has been recognized as a risk factor for decreased renal function and poor prognosis in IgA nephropathy in renal disea.

Hydroxychloroquine (HCQ) is considered an immunomodulatory and anti-inflammatory age.

Flowchart of path selection:

Methods: PubMed and Embase were systematically searched for studies through June 2021 comparing HCQ and other treatments to reduce proteinuria in patients with IgA nephropat.

method:

Forest plot comparing percent proteinuria reduction for HCQ and controls:

RESULTS: A total of 5 studies with 587 participants were includ.

result:

Forest plot comparing mean proteinuria levels at 6 months between HCQ and controls:

In conclusion, HCQ has a mild antiproteinuric effect in patients with IgA nephropathy

HCQ has mild antiproteinuric effect in patients with IgA nephropathy

Reference: Zhang J, Lu X, Feng J, Li H, Wang.

Reference: Zhang J, Lu X, Feng J, Li H, Wang.
Effects of Hydroxychloroquine on Proteinuria in IgA Nephropathy: A Systematic Review and Meta-Analys.
Biomed Res I.
2021 Dec 3;2021:917171 doi: 11155 /2021/917171 PMID: 34901280; PMCID: PMC866453 Leave a message here

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