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HCG during pregnancy those things
For sisters who are trying to conceive or have just become pregnant, HCG is definitely the focus of attention
.
In the first trimester, hCG rises rapidly, which can stimulate the corpus luteum to produce estrogen and progesterone, which is an important hormone for maintaining pregnancy, which can promote the decidua of the endometrium and maintain the stability
of uterine smooth muscle.
HCG can be detected throughout pregnancy, and levels of hCG can always be anxiety-provoking
.
Why is my HCG lower than others?
This is about the first anxiety of many pregnant mothers after pregnancy: How can someone else's double so good? Mine is still so low? Will the baby be bad?
Once the sperm and eggs combine and implant, trophoblasts at the implantation site produce and secrete HCG molecules, which can be detected in blood or urine 7 days after implantation or 12-14 days
.
It is worth noting that blood hCG levels vary greatly in different people of the same gestational age, and there is no comparison between individuals! For example, it is the 5th week of pregnancy, she 5000 you 2000, are within the standard range, we just don't "compare"
at all.
Women with healthy pregnancies may also have lower levels of hCG in the first trimester, so low hCG in the first trimester does not indicate a problem with the embryo, and a single abnormal hCG is worthless
.
Are we more concerned about whether your HCG has doubled than the value?
Does it matter if my HCG doubling is bad?
Blood hCG tends to double every 2-3 days for four weeks after embryo implantation, and the time required to double hCG may increase from 36 to 48 hours to 96 hours
as pregnancy progresses.
HCG peaks around 10 weeks' gestation, begins to decline at 17 weeks of gestational placental formation, and decreases below 5 mIU/ml after delivery
.
If doubling hCG is not good, especially if the 48-hour increase is <66%, then there is a high
probability of ectopic pregnancy or embryonic intrauterine pregnancy dysplasia.
But doubling is not good does not mean that it must be "not kept", if HCG is still on the rise, you can continue to follow up and observe
.
At 5 weeks of pregnancy, you can determine whether it is a normal pregnancy or an ectopic pregnancy
by ultrasound in the first trimester.
When the pregnancy is 6-7 weeks, if the ultrasound can see the fetal bud and the fetal heart tube beat, it means that the embryo is
developing.
What is low HG?
If the hCG is below the normal range, it is strongly recommended to repeat the hCG 48-72 hours after the initial examination to dynamically observe changes
in HCG.
If the rate and magnitude of hCG rise decreases significantly, the possible causes are:
1.
Ectopic pregnancy: Because the embryo implantation of ectopic pregnancy is outside the uterus, the "soil" for nourishment is not fertile enough, so the increase in HCG is insufficient
.
Suspected ectopic pregnancy should be actively presented, especially if there is abdominal pain or vaginal bleeding
.
2.
Possible embryo arrest: After embryo arrest, the activity of trophoblasts secreting HCG is insufficient, and there is a possibility of secondary spontaneous abortion, etc.
, which needs to be followed up in the outpatient clinic
.
3.
Biochemical pregnancy: mainly refers to the fertilized egg has not successfully implanted in the uterus and is pregnant with a "lonely"
.
Non-recurrent biochemical pregnancies do not require specific management, and follow-up to hCG after abortion is sufficient
.
4.
Normal pregnancy, wrong calculation of gestational age: Late ovulation in menstrual disorders may lead to incorrect calculation of gestational age
.
The level of change in follow-up HCG can be dynamically observed, and the gestational age size can also be determined
by combining intercourse time or B-ultrasound size.
Can HCG be too high also problematic?
Although hCG is very important in the first trimester, high hCG is not necessarily a good thing
.
When abnormally elevated hCG is detected, repeat hCG levels
within 48 to 72 hours are also recommended.
Possible causes of elevated hCG are: 1.
Multiple pregnancy: Multiple births may show higher HCG levels and stronger early pregnancy responses, but the doubling of hCG and the trend of change are similar
to those of singletons.
2.
Normal pregnancy, gestational age calculation error: Like low hCG, late ovulation in menstrual disorders may also lead to incorrect calculation of gestational age, and it is necessary to dynamically observe hCG or B-ultrasound to determine the size
of gestational age.
3.
Molar pregnancy: When the above two physiological conditions are excluded, molar pregnancy
should be considered.
A molar pregnancy is not pregnant, but a lesion of the trophoblasts that produce HCG, and excessive proliferation of trophoblasts can lead to abnormally high
levels of hCG.
If there is excessive early pregnancy reaction or excessive hCG levels, you can ask a doctor for help in the gynecological clinic
.
Although HCG is an important indicator of early pregnancy, combined with numerical values and growth trends to help doctors diagnose, HCG is not the only judgment index, often need to be combined with B ultrasound to judge
.
For pregnant mothers who do not double their hCG, they may want to adjust their hCG levels
with medication.
Although progestogen insufficiency can be supplemented with progestogens for threatened miscarriage or to prevent preterm birth, hCG deficiency can only be observed dynamically and cannot be relied upon with medical supplementation
.
Miscarriage or biochemical pregnancy during early pregnancy is mostly related to the quality of the embryo itself, and there is no need to be too anxious
.