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Hansen Pharma's high-priced broad-spectrum antifungal drug was approved for Phase III clinical trials

 Last Update: 2022-01-11
 Source: Internet
 Author: User

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Article source: Medical Rubik's Cube Info

Author: Sunshine

On December 16, Hansen Pharmaceutical issued an announcement stating that the Phase III clinical trial of Ibrexafungerp tablets was approved by the CDE for the treatment of vulvovaginal candidiasis (VVC)

In February 2021, Hansen Pharmaceuticals and Scinexis signed an agreement to obtain the exclusive license to research, develop and commercialize ibrexafungerp in the People’s Republic of China (including Hong Kong, Macau and Taiwan).

Vaginal yeast infection is a kind of fungal infection, the symptoms are vulvar itching, burning pain, etc.

In June 2021, ibrexafungerp (trade name: Brexafemme) was approved by the US FDA for the treatment of vulvovaginal candidiasis, becoming the first new antifungal approved in more than two decades, and the first and only vagina Non-azole therapy for yeast infections

Ibrexafungerp is a world-first glycogen synthase inhibitor with a novel triterpenoid structure with a novel mechanism of action.

At present, multiple indications of Ibrexafungerp are in the late stage of clinical development, including nosocomial infections mainly caused by Candida (including Candida auris) and fungi such as Aspergillus

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