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Haisco introduces Lorecivivint, a new osteoarthritis drug for US$140 million

 Last Update: 2021-09-19
 Source: Internet
 Author: User

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On September 13, Haisco announced the signing of a cooperation agreement with Biosplice Therapeutics of the United States for the treatment of osteoarthritis, the first innovative drug Lorecivivint, and obtained Lorecivivint's exclusive development, registration and commercialization rights in China
.

To this end, Haisco will pay Biosplice US$20 million in down payment and registration mileage, as well as a certain amount of commercial mileage and royalties based on future sales, with a total transaction amount of US$140 million

Lorecivivint is a drug that is being developed by Biosplice to improve osteoarthritis, and it may become the first innovative drug approved for the improvement of bone and joint function in recent years
.

It is a CLK/DYRK kinase inhibitor that regulates the Wnt pathway and is currently undergoing phase III clinical trials for the treatment of knee osteoarthritis in the United States

According to related research reports, an estimated 303 million people worldwide were affected by osteoarthritis in 2017, of which the knee is the most common site of osteoarthritis
.

It is estimated that 14 million people in the United States suffer from symptomatic knee osteoarthritis (KOA).

Biosplice Therapeutics is an American biotechnology company focusing on innovative drugs at the clinical stage, dedicated to providing treatments based on selective precursor mRNA splicing for major diseases
.

The company is currently developing the first small molecule therapy based on selective precursor mRNA cleavage, and Lorecivivint for the treatment of osteoarthritis is in clinical phase III

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