-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Proton pump inhibitors (PPIs) are one of the 10 most commonly used drugs in the world.
PPIs are generally recommended for the treatment of diseases associated with hypersecretion of gastric acid, such as gastroesophageal reflux disease, medsci.
Recent studies have shown that PPIs can affect the intestinal microbial community by changing the natural gastrointestinal environment.
PPIs can affect the intestinal microbial community by changing the natural gastrointestinal environment.
Type 2 diabetes (T2DM) has become a global epidemic, with a global prevalence rate of 8.
The relationship between diabetes and "brain gut axis" and gut microbes
The relationship between diabetes and "brain gut axis" and gut microbesIn view of the significant impact of PPIs on the gut microbiota, its use may increase the risk of T2DM.
In view of the significant impact of PPIs on the gut microbiota, its use may increase the risk of T2DM.
A total of 204,689 non-diabetic participants participated in the Nurses’ Health Study (NHS), NHS Phase II, and Health Professional Follow-up Study (HPFS).
diagnosis
During the study period, more than 2127471 person-years of follow-up and 10105 diabetes events were recorded.
Compared with people who use PPIs less often, participants who regularly take PPIs have a 24% higher risk of diabetes (HR=1.
The duration of routine use of PPIs and the risk of T2DM.
The duration of routine use of PPIs and the risk of T2DM.
Even more surprising is that the risk of diabetes increases with the duration of the use of PPIs.
It can be seen that the frequent use of PPIs is related to the high risk of T2DM, and the risk increases with the use of time.
references:
bmj.
bmj.
com/content/70/6/1070" target="_blank" rel="noopener">Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies.
Leave a message here
