Gut: The intestinal bacteria may not be involved in the onset of gestational diabetes in women.

September 14, 2020 // -- Maternal overweight and obesity increase an individual's risk of developing gestational diabetes, and recently researchers found that intestinal bacterial composition is directly related to the body's overweight and the occurrence of a range of metabolic diseases, but researchers do not know whether intestinal bacteria are also involved in the development of gestational diabetes; In a study published in the international journal Gut, scientists from the University of Turku and others conducted a clinical trial to investigate the effects of two food supplements, fish oil and probiotics (containing HN001 of Bacillus glycobacteria in rats and lactobacillus 420 in animals) on individuals with gestational diabetes.
Photo Source: In the CC0 Public Domain study, researchers analyzed 270 stool samples from overweight and obese female bodies using advanced analysis and bio-information based on deep sequencing macrogenomic analysis;
researchers found that the composition and function of gut microbes may not be involved in the development of gestational diabetes in obese and overweight women, and that there did not appear to be any difference in the gut microbiome of women with gestational diabetes compared to women without gestational diabetes.
We all know that probiotics can affect the composition of the gut bacteria, but rarely analyze how the combination of probiotics and fish oil affects the gut bacteria, so the researchers randomly divided the participants into four groups of researchers: fish oil and placebo, probiotics and placebos, fish oil and probiotics and placebos, and these women were taking supplements from early pregnancy until after natal.
Interestingly, the results of this paper show that the combination of fish oil and probiotics regulates the composition of the body's gut microorganisms, especially in women who do not have gestational diabetes, although later researchers need further research to analyze whether the gut microbiomes of women with gestational diabetes are less likely to be modified or improved with food supplements.
() Original source: Kati Mokkala, Niklas Paulin, Noora Houttu, et al. Metagenomics analysis of gut microbiota in response to diet intervention and gestational diabetes in overweight and obese women: a randomised, double-blind, placebo-controlled clinical trial, Gut (2020). DOI:10.1136/gutjnl-2020-321643.