GUT: The effect of Helicobacterrobacteria eradication on the incidence and mortality of stomach cancer.

Stomach cancer is closely related to H.pylori infection.
previous systematic review and meta-analysis of the study concluded that eradication and treatment reduced the future incidence of stomach cancer, but its degree is uncertain, gastric cancer-related mortality has not decreased.
as more data accumulate, researchers recently updated their findings, and they assessed the impact of eradication treatment on the future risk of stomach cancer in patients with endoscopic mucosa removal of stomach tumors.
researchers searched the medical literature as of February 2020 for a randomized controlled study (RCTs) on the risk of subsequent stomach cancer in adults who were positive for healthy Helicobacter pyridobacteria and patients who received endoscopic mucosa removal.
control group received or did not receive a placebo, followed for more than 2 years, and assessed the effects of treatment interventions on disability-adjusted life years (Dalys).
a total of 10 randomized controlled studies, seven included 8,323 healthy Helicobacter pyrobacteria-positive adults, and three studies included 1,841 Helicobacter pyridosis-positive stomach tumor patients.
in health-positive adults, eradication and treatment reduced the incidence of stomach cancer (RR=0.54) and the risk of gastric cancer death (0.61), but had no significant effect on all-cause mortality.
data show that if Helicobacter pyridosis screening and treatment were implemented globally, 8743815Daly would be reduced.
for patients with positive stomach tumors, eradication treatment also reduced the recurrence rate of future stomach cancer (RR-0.49).
meta-analysis shows that there is moderate evidence that Helicobacterrobacteria eradication treatment can reduce the incidence of subsequent stomach cancer in people with health and stomach tumor-positive infections, as well as reduce gastric cancer-related mortality.
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