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How to divide a pill into 1/3 or even smaller? Many parents will encounter similar problems when giving medicine to their children.
In fact, problems such as inaccuracy and unsafety caused by "guessing the dose and breaking the medicine" have always been the pain points of pediatric medication.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
awkward
"Children's discretion" is too broad
"Estimate" the medicine is based on feeling
Recently, Xu Ning is worrying about his child taking medicine.
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
Also stumped by the instructions is Ding Ran, the mother of a 6-year-old child.
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
In fact, even with a clear usage and dosage, many parents are still stuck in the matter of medicine dispensing.
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
In order to be as precise as possible, Cheng Wei simply poured out one bag and divided it into roughly equal four parts.
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
In this regard, Liu Tong's approach seems quite bold-each time he only eats the separated part, and not the rest.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
For tablet drugs, the difficulty of dispensing is that the tablets are too small and it is difficult to fix the position by hand.
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Hidden danger
Can you be particular about it?
Save and use, guarantee against difficulties
Parents who feel "big heads" about drug distribution turn to the Internet to find solutions, and a dazzling array of "artifacts" for drug distribution have emerged as the times require.
The reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
The reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
Take a closer look at these medicine dispensing tools, and some are in the shape of a flat box with multiple compartments inside.
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
The principle is very simple, and the promotional image is also displayed quite perfect, but from the buyer's comments, there are still many limitations in the dispenser.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
"The cap with a blade is loose, and the blade cannot cut the medicine in half.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
Even if the medicine dispenser succeeds in dividing the tablet into two halves, if you want to continue to divide the tablet, it is likely that the "artifact" is powerless.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
"Some parents try to dispense medicines at home, which may cause many hidden dangers of medication safety.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
"Even if it is a medicine that can be divided, it is difficult for parents to ensure that the distribution is accurate, stored well, and used correctly.
" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
Suggest
Rich choice of dosage forms
Professional dispensing service
According to the data from the 2016 Children’s Drug Safety Survey Report issued by the Southern Institute of Medicine and Economics of the State Food and Drug Administration , etc.
, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
Zhao Zhigang believes that there is an imbalance in the supply of medicines for children in my country.
Among them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
Among them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
However, drug distribution has certain technical requirements.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
In this regard, the Children's Hospital of Zhejiang University School of Medicine has made more active explorations.
Its pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
Its pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
"The work of dispensing medicine itself requires investment of manpower and material resources.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
How to divide a pill into 1/3 or even smaller? Many parents will encounter similar problems when giving medicine to their children.
In fact, problems such as inaccuracy and unsafety caused by "guessing the dose and breaking the medicine" have always been the pain points of pediatric medication.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
awkward
"Children's discretion" is too broad
"Estimate" the medicine is based on feeling
Recently, Xu Ning is worrying about his child taking medicine.
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
Also stumped by the instructions is Ding Ran, the mother of a 6-year-old child.
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
In fact, even with a clear usage and dosage, many parents are still stuck in the matter of medicine dispensing.
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
In order to be as precise as possible, Cheng Wei simply poured out one bag and divided it into roughly equal four parts.
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
In this regard, Liu Tong's approach seems quite bold-each time he only eats the separated part, and not the rest.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
For tablet drugs, the difficulty of dispensing is that the tablets are too small and it is difficult to fix the position by hand.
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Hidden danger
Can you be particular about it?
Save and use, guarantee against difficulties
Parents who feel "big heads" about drug distribution turn to the Internet to find solutions, and a dazzling array of "artifacts" for drug distribution have emerged as the times require.
The reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
The reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
Take a closer look at these medicine dispensing tools, and some are in the shape of a flat box with multiple compartments inside.
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
The principle is very simple, and the promotional image is also displayed quite perfect, but from the buyer's comments, there are still many limitations in the dispenser.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
"The cap with a blade is loose, and the blade cannot cut the medicine in half.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
Even if the medicine dispenser succeeds in dividing the tablet into two halves, if you want to continue to divide the tablet, it is likely that the "artifact" is powerless.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
"Some parents try to dispense medicines at home, which may cause many hidden dangers of medication safety.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
"Even if it is a medicine that can be divided, it is difficult for parents to ensure that the distribution is accurate, stored well, and used correctly.
" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
Suggest
Rich choice of dosage forms
Professional dispensing service
According to the data from the 2016 Children’s Drug Safety Survey Report issued by the Southern Institute of Medicine and Economics of the State Food and Drug Administration , etc.
, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
Zhao Zhigang believes that there is an imbalance in the supply of medicines for children in my country.
Among them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
Among them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
However, drug distribution has certain technical requirements.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
In this regard, the Children's Hospital of Zhejiang University School of Medicine has made more active explorations.
Its pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
Its pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
"The work of dispensing medicine itself requires investment of manpower and material resources.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
How to divide a pill into 1/3 or even smaller? Many parents will encounter similar problems when giving medicine to their children.
In fact, problems such as inaccuracy and unsafety caused by "guessing the dose and breaking the medicine" have always been the pain points of pediatric medication.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
Experts point out that children are not "miniature adults", and if imitating adult drug use methods, it may become a safety hazard.
awkward
awkward "Children's discretion" is too broad
"Children's discretion" is too broad "Estimate" the medicine is based on feeling
"Estimate" the medicine is based on feeling Recently, Xu Ning is worrying about his child taking medicine.
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
My 3-year-old daughter had a cough, and thought of the honey condensed Chuanbei loquat ointment at home.
The adult had good results after eating it, so she planned to give it to her child.
"The instructions say that adults take one tablespoon (15 ml) three times a day, and children halve it.
But the definition of "children" is too broad.
There is so much difference between the age of 3 and the age of 10.
half?"
Also stumped by the instructions is Ding Ran, the mother of a 6-year-old child.
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
"Many instructions do not clearly indicate the usage and dosage of children at all.
At most, there is a sentence of'children's discretionary reduction', but it is really difficult to judge how much to reduce.
"
In fact, even with a clear usage and dosage, many parents are still stuck in the matter of medicine dispensing.
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
Not long ago, due to the child's loss of appetite, Cheng Wei took his 10-month-old son to the hospital.
The doctor prescribed compound pepsin powder to aid digestion.
"According to the usage and dosage in the instructions, 0.
75 grams once under the age of one year, and the size of a bag is 3 grams, which means that only a quarter of the amount can be poured at a time.
But there is no such accurate balance at home that can weigh and pack.
The bag is also opaque, and it can only be estimated by feeling every time.
The result is either more or less.
"
In order to be as precise as possible, Cheng Wei simply poured out one bag and divided it into roughly equal four parts.
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
But after eating one serving, how to keep the remaining three servings became a problem again.
"It feels unhygienic after doing this, and it is easy to get damp.
I am worried that the efficacy of the medicine will be affected.
"
In this regard, Liu Tong's approach seems quite bold-each time he only eats the separated part, and not the rest.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
"Wasting a little is better than losing the medicine.
" For the capsule medicine, she also opened the capsule, felt the part needed and put it back into the capsule for taking, and threw the rest away.
For tablet drugs, the difficulty of dispensing is that the tablets are too small and it is difficult to fix the position by hand.
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Some tablets have bulges in the middle, and the material is not suitable for cutting.
It is often cut with a single cut, and it will be uneven in size if it is slightly offset, or even broken into more small pieces.
"If this is the case, I can only crush it even more, and then allocate it to the children for food.
"
Hidden danger
Hidden danger Can you be particular about it?
Can you be particular about it? Save and use, guarantee against difficulties
Save and use, guarantee against difficulties Parents who feel "big heads" about drug distribution turn to the Internet to find solutions, and a dazzling array of "artifacts" for drug distribution have emerged as the times require.
The reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
Medicine, medicine, medicineThe reporter conducted a search on the Internet platform using "drug dispenser" as the key word, and there were a large number of drug-dispensing tools of different shapes and colors, basically aimed at the most difficult to cut flaky drugs .
Take a closer look at these medicine dispensing tools, and some are in the shape of a flat box with multiple compartments inside.
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
Some are in the shape of a vertical medicine bottle, and the upper and lower multilayer structures can be twisted to separate each other.
In addition to the difference between whether they can store medicines and whether they bring their own miniature water cups to facilitate medication, the core components of these dispensers are the clips built into the bottom and the blades built into the lid.
When the medicine is divided, the tablet is fixed with a clip, and the box cover is pressed down, and the blade will cut the tablet in half in a manner similar to a "guillotine".
The principle is very simple, and the promotional image is also displayed quite perfect, but from the buyer's comments, there are still many limitations in the dispenser.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
For example, the medicine can only be divided into two halves.
If it is cut further, it is difficult to fix it due to its uneven shape.
In addition, tablets that are too large or too small are not easy to cut, and sugar-coated tablets are also easy to break.
"The cap with a blade is loose, and the blade cannot cut the medicine in half.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
" "The workmanship is not good, and the cut tablets directly turn into slag.
" "The cap of the cut tablet is very loose, and the cover of the larger one is crooked.
The pill is not divided into two halves, just smashed directly".
.
.
Take a four-in-one medicine dispenser that has been purchased by nearly 10,000 people as an example, there are many "difficult to use" voices in the comments.
Even if the medicine dispenser succeeds in dividing the tablet into two halves, if you want to continue to divide the tablet, it is likely that the "artifact" is powerless.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
A study from the Chinese Pharmacy Conference and the 13th Chinese Pharmacist Week Proceedings shows that 7 different sizes of tablets are divided into half and quarter using four splitting methods: hand, scissors, blade, and medicine cutter.
Splitting; refer to the European Pharmacopoeia half-pill split-dose evaluation standard to evaluate the splitting situation of this tablet.
The results showed that in the splitting test of 7 kinds of tablets, 5 kinds passed the splitting test by the medicine cutter, and the quarter-split tablets failed the test by four splitting methods.
"Some parents try to dispense medicines at home, which may cause many hidden dangers of medication safety.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
" Zhao Zhigang, director of the pharmacy department of Beijing Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Management Center, pointed out that which drugs can be divided and which cannot be divided.
Professional pharmacists come to judge.
Once some medicines are separated, the original structure will be destroyed and the efficacy of the medicine itself will be affected.
For example, sustained-release tablets, if taken separately, the sustained-release mechanism may be destroyed, and the drug may be released suddenly, leading to poisoning.
"Even if it is a medicine that can be divided, it is difficult for parents to ensure that the distribution is accurate, stored well, and used correctly.
" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
Adverse reactions adverse reactions adverse reactions" Zhao Zhigang said that children of different ages vary greatly, and the dosage of drugs cannot simply be halved by parents' feelings.
In addition, different drug units are different, some are in milliliters, and some are in milligrams.
Once the parents confuse the drug, the consequences will be very serious, resulting in overdose.
Previously, studies have found that the incidence of adverse drug reactions in children in China is close to twice that of adults, and the incidence of adverse drug reactions in neonates is closer to four times that of adults.
Suggest
Suggest Rich choice of dosage forms
Rich choice of dosage forms Professional dispensing service
Professional dispensing serviceAccording to the data from the 2016 Children’s Drug Safety Survey Report issued by the Southern Institute of Medicine and Economics of the State Food and Drug Administration , etc.
, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
Medicine Medicine Medicine, among the 176652 domestic drug approvals, only 3,517 are drugs intended for children (child-specific drugs refer to the generic name The medicines that clearly specify children's medicines do not include medicines that are used for children but do not indicate that they are children's medicines in the generic name), accounting for only 2%.
In terms of varieties, among the more than 3,500 conventional medicines, there are only more than 60 special varieties for children.
Zhao Zhigang believes that there is an imbalance in the supply of medicines for children in my country.
Among them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
Over -the-counter drugs over -the-counter drugsAmong them, the number of over -the-counter medicines for common diseases has increased significantly, and some areas even appear to be surplus.
However, the prescription drugs required for the treatment of tumors, neurological diseases and rare diseases are seriously insufficient, mainly due to the lack of varieties, dosage forms, and specifications suitable for children.
The vast majority of drug instructions lack the indications and dosage for children.
"Because of the lack of clinical trials in children and insufficient relevant research data, doctors often have to explain the situation in advance with the children's family members, combined with medication experience, based on adult doses, and convert the doses required by children according to indicators such as weight or age.
"
However, drug distribution has certain technical requirements.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
Zhao Zhigang believes that corresponding specifications should be introduced and specific operating standards should be formulated, which should be completed by professional pharmacists.
Under the condition of ensuring that the sanitary conditions meet the standards, the balance should be weighed with precision instruments and stored properly to clarify the shelf life.
In this regard, the Children's Hospital of Zhejiang University School of Medicine has made more active explorations.
Its pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
Hospital hospital hospitalIts pharmacy department has set up a special drug subcontracting post, where two full-time pharmacists grind the tablets every day, and pack them into small packaging bags according to specifications ranging from one-third to one-sixteenth.
.
Mark the date of subcontracting with markers of different colors and put them in a sealed box for use by children who are hospitalized in the hospital.
Of course, the cost of consumables and personnel for carrying out sub-assembly work can only be supported by departments and hospitals for the time being.
"The work of dispensing medicine itself requires investment of manpower and material resources.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
In many developed countries, drug dispensing services are compensated by separate fees.
Generally, the fee for dispensing medicines for children is higher than that for adults, because dispensing requires precise dispensing and is more complicated.
"In Zhao Zhigang's view, if we want to solve the problem of children's drug shortage, we should start from many aspects.
"Children’s drug research and development cannot be accomplished overnight.
A more realistic approach is to produce more convenient dispensing and use dosage forms, such as liquid dosage forms, granular dosage forms, etc.
, on the basis of existing drugs, and provide specifications suitable for children (such as microtablets).
), and implement the pharmacy service compensation mechanism (children’s medication adjustment fee) as soon as possible, and hand over professional matters to professional pharmacists, so as to ensure the safety of children’s medication.
