Guangyao group takes the lead in entering the era of traditional Chinese medicine gene

Important breakthroughs have been made in the study of traditional Chinese medicine in China Yesterday, Guangyao group and Chinese Academy of Medical Sciences jointly announced in Diaoyutai State Guesthouse in Beijing that the "Danshen genome framework map" was successfully completed This is the first framework map of medicinal plant genome released in the world, which means Guangyao group is the first to enter the era of traditional Chinese medicine gene in the world According to reports, the Baiyunshan Danshen genome project started five years ago, and was jointly carried out by Guangzhou Baiyunshan Heji Huangpu traditional Chinese Medicine Co., Ltd., a subsidiary of Guangzhou Pharmaceutical Group, and the Institute of medicinal plants, Chinese Academy of Medical Sciences So far, the total investment of the project has exceeded 30 million yuan The second generation high-throughput sequencing technology was used to sequence the whole genome of Salvia miltiorrhiza and complete the assembly of the genome framework map of Salvia miltiorrhiza At present, the sequencing depth has reached 20 times of the genome size of Salvia miltiorrhiza, and the sequencing results have covered 92% of the whole genome and 96% of the gene coding region of Salvia miltiorrhiza Chen Shilin, director of the Institute of medicinal plants of the Chinese Academy of Medical Sciences, said that traditional Chinese medicine used to be the most systematic and advanced medical theoretical system in the world However, due to the lack of effective communication between traditional Chinese medicine and modern medicine, this ancient medicine has gradually been marginalized The genome project of traditional Chinese medicine is such a bridge to bridge the gap between traditional Chinese medicine and Western medicine This research will not only help the world to understand traditional Chinese medicine and accelerate the internationalization of traditional Chinese medicine, but also take the initiative in the international competition by applying for international patents Li Chuyuan, head of Guangyao group, said that for a long time, Westerners didn't accept traditional Chinese medicine because people couldn't figure out which components Chinese medicine was made of and which were effective The study of modernization of traditional Chinese medicine has made people's understanding of traditional Chinese medicine develop from the initial shape discrimination to physical and chemical analysis, then to fingerprint analysis, and now to a deeper level of gene analysis In this way, the mechanism of the action of traditional Chinese medicine can be explained by modern scientific language Another important significance of the research results is that gene technology can be used to increase the production of traditional Chinese medicine and promote the sustainable development of traditional Chinese medicine resources At the conference, the two sides also announced that on the basis of completing the whole genome of Salvia miltiorrhiza, the research platform of the Institute of medicinal plants will be used to further expand gene research to the base plants of many well-known products of Guangyao group, thus opening the curtain of strategic research on the overall layout of Chinese medicine resources of Guangyao group.