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Grapefruit + lipid-lowering drugs eat "myolysis"?

 Last Update: 2021-07-25
 Source: Internet
 Author: User

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It's the season when grapefruit is on the market in large numbers, and it is loved by many people because of its rich nutrition and the effects of removing fire and relieving cough

"Rhabdomyolysis refers to the damage of striated muscle cells caused by physical, chemical, biological or pharmaceutical factors.

The bergamot in grapefruit can inhibit the metabolism of some drugs

According to Jin Rui, grapefruit contains "bergamot", which inhibits CYP3A4 metabolic enzymes.

"In theory, in addition to atorvastatin, other drugs that need to be metabolized by CYP3A4 metabolic enzymes will be affected by grapefruit, such as statins, simvastatin, lovastatin, etc.

Avoid large amounts of grapefruit and grapefruit juice when taking medicines

"Grapefruit (grapefruit) and ordinary grapefruit are both of the citrus genus of the Rutaceae family, but the types are different

Jin Rui recommends that for safety reasons, avoid ingesting a large amount of grapefruit juice or grapefruit when taking the medicine, so as to avoid the increase of the blood concentration of the medicine in the body or the increase of side effects

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