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Exercise can prevent many cancers, but did you choose the right time of day? Disturbing the body's circadian rhythm increases cancer risk
.
Recently, two studies found that exercising early in the morning seemed to prevent breast and prostate cancer
better than exercising later in the day.
Nocturnal exercise appears to have a moderate protective effect
against prostate cancer.
Morning physical activity was associated with a reduced risk of cardiovascular disease, regardless of overall physical activity, highlighting the potential importance
of temporal activity in cardiovascular disease prevention.
Overall, exercising at 8-10 a.
m.
can not only reduce cancer risk by 27%, but also stroke by 17%.
This article is the original of Translational Medicine Network, please indicate the source for reprinting
Written by Sophia
Exercise and cancer
01
In this study, the researchers observed that the overall protective effect of recreational and home physical activity on cancer may vary
depending on the time of day of the activity.
Studies have found that early morning activity may be more protective than morning and afternoon activity for the potential risk of breast and prostate cancer
.
The findings of evening activity differed, with only moderate protection against prostate cancer observed
.
There is no consistent pattern between different time types, and differences
are observed in tumor subphenotypes.
Studies estimated odds ratios (OR) and 95% confidence intervals (95% CI)
for different duration of activity.
Early morning (8-10 am) activity was protective against breast (OR = 0.
74, 95% CI = 0.
48 to 1.
15) and prostate cancer (OR = 0.
73, 95% CI = 0.
44 to 1.
20) compared with no physical activity; The combined meta-OR for the two cancers was 0.
74 (95% CI = 0.
53 to 1.
02).
No effects of breast or prostate cancer were observed during the late-morning to afternoon activities, while protective effects were also observed for nocturnal activities of prostate cancer only (OR = 0.
75, 95% CI = 0.
45-1.
24).
For both cancers, the protective effect of early morning activity is more pronounced
in the mid/evening period.
Obesity is associated with breast and prostate cancer and may be an additional pathway
associated with physical activity and physical activity time in relation to reduced cancer risk.
The route is unclear and may be related to
circadian hormonal patterns.
The researchers observed that people who exercised in the morning experienced higher weight loss and lower total calorie consumption
compared to exercising at other times of the day.
However, adjusting for BMI and total calorie consumption did not change the cancer risk pattern
for time categories in our analysis.
Overall, the findings suggest that time of day is an important aspect of physical activity and may enhance physical activity's protective effect
against cancer risk.
In future studies, the effect of physical activity time on cancer risk should be examined and activity patterns assessed in more detail, including occupational activity
.
More evidence is needed on the biological mechanisms by which time of physical activity affects circadian rhythms, and further research into the potential mechanisms
underlying the potential effect of timing on cancer risk should be conducted.
Exercise and cardiovascular disease
02
Cardiovascular disease (CVD) is the most common cause of
death worldwide.
The prevalence of cardiovascular diseases is expected to rise further due
to reasons such as physical inactivity, obesity, diabetes, high blood pressure, high cholesterol and blood lipid levels, and the number of elderly people.
Physical activity is an important stepping stone to healthy aging and is theoretically easy for most people to regulate
.
Currently, little is known about the effect of time spent on daily physical activity (referred to here as "time activity") on the risk of cardiovascular disease (CVD
).
This study recruited 502 490 participants aged 40-69 years between 2006 and 2010 and is a large population-based prospective cohort study
.
To group participants based on physical activity time, the researchers performed K-means clustering using a 24-hour mean
.
This prospective observational study identified several different physical activity time subgroups in the UK general population, similar to participants
with different types of time activity.
The study found that subjects most active in the morning had a lower risk of CAD and stroke, independent of
average daily physical activity levels.
In particular, participants who did the most daily physical activity in the late morning had a 16 percent lower risk of CAD and a 17 percent
lower risk of stroke.
Overall, studies have shown that a greater proportion of physical activity in the morning is associated with
a lower risk of CVD, regardless of average total physical activity.
The study provides the first evidence from a large population database and suggests a new term time activity and insights
into the seemingly positive effects of morning physical activity on cardiovascular disease risk.
When validated and broadly metabolically characterized, these current results may suggest that time-dependent physical activity interventions may be an additional beneficial behavioral factor to achieve maximum health benefits and reduce the risk of
cardiovascular disease.
Resources:
https://doi.
org/10.
1002/ijc.
33310
https://doi.
org/10.
1093/eurjpc/zwac239
Note: This article is intended to introduce the progress of medical research and cannot be used as a reference
for treatment options.
If you need health guidance, please go to a regular hospital
.
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