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As the population continues to age, the incidence of early gastric cancer (EGC) is increasing
.
Early gastric cancer refers to the cancer tissue limited to the gastric mucosa and submucosa, regardless of its size and lymph node metastasis
The purpose of this study was to elucidate the indications and prognosis of endoscopic resection (ER) in middle-aged and elderly patients with early gastric cancer in terms of life expectancy
.
.
The researchers recruited patients with early gastric cancer ≥ 75 years old who were treated with ER from 4 medical institutions from January 2007 to December 2012, and collected clinical data of the patients undergoing endoscopic resection, including the ECOG table.
Type status (ECOG-PS), Charlson comorbidity index (CCI) and prognostic nutritional index (PNI)
.
The primary outcome measure was overall survival (OS)
Survival of patients with different indicators
Survival of patients with different indicatorsA total of 400 patients with early gastric cancer were consecutively recruited, with a mean age of 79.
3 years (range 75-93 years)
.
The median follow-up was 5.
The median follow-up was 5.
Different prognostic assessments of patients tested
Different prognostic assessments of patients testedIn multivariate analysis, ECOG-PS score 2-4, PNI < 49.
1, and endoscopic cure probability (eCura) C-2 were independent predictors of patient outcome (hazard ratios were 8.
84, 2.
49, and 1.
79, respectively)
.
The 5-year OS rate for patients without these prognostic factors was 90.
To sum up
.
Endoscopic resection may prolong survival in elderly patients with early gastric cancer
Endoscopic resection may prolong survival in elderly patients with early gastric cancer Endoscopic resection may prolong survival in elderly patients with early gastric cancer
Original source:
Original source:Waki Kotaro,Shichijo Satoki,Uedo Noriya et al.
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