Gastroenterology: birth patterns, diet, and specific diseases and changes in gut microbes

Infancygastricintestinal microbes affect the development ofimmunesystem, changes in the microbiome in early life may help to reduce the risk ofimmunediseaseRecently, researchers examined the relationship between maturity and subsequent allergies in the microbiome of infants andchildrenstudy recruited 440childrento collect 1,453faecessamples between 5, 13, 21, 31 weeks and 6-11 years of age after birthAmong the children in the study, 49.3 per cent were girls, the caesarean section rate was 24.8 per cent, all but six were breastfed to varying degrees, and the child was 40 weeks oldThe main endpoints of the study were data on topical dermatitis, school-age allergies and asthma under 3 years of agestudies used the Shannon index to assess the diversity offecesmicrobial systems, with no significant difference between 5 and 13 weeks after birth, but changed after 21-31 weeksMost bacteria with bacillus and filithnobacteria already exist 5 weeks after birth, while thick-walled bacteria are acquired in the late infancyDuring school age, many new line bacteria, thick-walled bacteria and bacteria are presentThe fastest period of increase in microbiodiversity was 31 weeks after deliveryVaginal delivery, compared with caesarean section, is closely related to the enrichment of the bacterial species of 5-31 weeks, especially the polymorphic bactus genusFrom 13 weeks onwards, diet has become the most important factor in determining microbial composition - interrupting breastfeeding, rather than introducing solid foodsAfter the interruption of breast milk, the levels of Bifidobacteria, Staphylococcus and streptococcus decreased, while the levels of spirulina increasedAfter adjustment, the study found that fecal microbial composition was associated with atopic dermatitis, allergies and asthma, and that spirulina, ethmolytes and bacillus were all associated with reduced risk of atopic syndromestudies have found that changes in theand composition of the intestinesin infants and children are associated with allergies and asthma risks