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    Home > Active Ingredient News > Antitumor Therapy > Gastric Cancer: Efficacy and safety of ramucirumab in the treatment of advanced gastric cancer: a post-marketing observational real-world study from Japan

    Gastric Cancer: Efficacy and safety of ramucirumab in the treatment of advanced gastric cancer: a post-marketing observational real-world study from Japan

    • Last Update: 2021-06-04
    • Source: Internet
    • Author: User
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    Gastric cancer is one of the most common malignant tumors in the world.


    Gastric cancer is one of the most common malignant tumors in the world.


    The study is a single-arm, prospective, multi-center, non-interventional post-marketing observational study.


    The study is a single-arm, prospective, multi-center, non-interventional post-marketing observational study.


    The study included 687 patients, of which 658 patients met the analysis of the study.


    Most patients in the ramucirumab combination therapy group and ramucirumab monotherapy group had adverse events ≥ 1 (combination group: any grade, 479/528; 90.



    Common adverse events

    At 6 months, 490 (74.


    At 6 months, 490 (74.



    Proportion and reason of ramucirumab interrupted treatment

    The median survival time of single-agent treatment and combination treatment was 5.


    The median survival time of single-agent treatment and combination treatment was 5.



    subsistence analysis

    In summary, this Japanese real-world study shows that the efficacy and safety of ramucirumab in the treatment of advanced gastric cancer are consistent with clinical studies.


    In summary, this Japanese real-world study shows that the efficacy and safety of ramucirumab in the treatment of advanced gastric cancer are consistent with clinical studies.


    Original source:

    Yucherng Chen, Taeko Katayose, Soshi Nagaoka, et al.


    Yucherng Chen, Taeko Katayose, Soshi Nagaoka, et al.
    A post-marketing observational study of ramucirumab in patients with gastric cancer in Japan.
    Gastric Cancer.
    2021 May 28.
    doi: 10.
    1007/s10120-021-01199-0.
    Online ahead of print.


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