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| Gao Fu et al. Since 1878, many suspected HPAIV outbreaks have been recorded worldwide. Since the end of 2019, highly pathogenic H5Ny avian influenza has frequently occurred in birds in Eurasia and Africa. Academician of the Academy of Sciences Shi Weifeng and Gao Fu specifically pointed out in the article that the H5N8 avian influenza virus is pandemic in Asia, Europe and Africa, and it has become an important issue affecting global poultry breeding and wildlife safety. At the same time, H5N8 avian influenza outbreaks have also occurred in poultry and wild birds in the Middle East (Israel) and East Asia (Japan and South Korea). Up to now, the areas affected by the H5N8 bird flu epidemic are still increasing, and at least 46 countries have reported the H5N8 highly pathogenic bird flu epidemic. What has aroused the vigilance of the outside world is that in December 2020, Russia reported that 7 farm workers were infected with the H5N8 avian influenza virus. The authors stated in the article that due to the long-distance migration of wild birds, the innate recombination ability of avian influenza virus (AIV), the enhancement of human receptor binding ability and the continuous variation of HPAIV antigen, the global spread and potential risk of H5N8 AIV It poses a serious threat to poultry farming, wildlife and global public health. The authors therefore point out that monitoring of HPAIV in poultry farms, live poultry markets, and wild birds should be restored to pre-COVID- 19 pandemic or higher levels. 19 big In addition, the transmission, pathogenicity and antigenicity of 2. The authors also emphasized that education and publicity are also very important, including strengthening personal protection measures during the flu season, staying away from wild birds, and avoiding hunting and eating wild birds. This research was funded by the National Science and Technology Major Project (2018ZX10101004), Shandong First Medical University Academic Promotion Plan (2019QL006) and Shandong Taishan Scholars Project. Article link: https://science.
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