Ganoderma spore oil can induce cancer stem cell death

Recently, at the 2010 Southern edible fungus industry development summit forum hosted by Guangdong edible fungus industry association and Guangdong Institute of Microbiology and hosted by Guangdong Guangdong micro edible fungus Technology Co., Ltd., Yang Baihua, a professor of the University of Toronto, Canada, made a breakthrough in the research of Ganoderma lucidum spore oil inhibiting tumor stem cells, which attracted great attention Yang Baihua is also a visiting professor of Guangdong Institute of microbiology According to Yang Baihua, stem cells are the germinating place and persistent carrier of cancer According to the theory of tumor stem cells, only a small part of the tumor stem cells have the ability of proliferation and metastasis The tumor originates from these cells, while the rest of the tumor cells do not have the ability of proliferation and metastasis In other words, the only real threat to human health is cancer stem cells Although these cells account for a very small proportion of all tumor cells, they are the source of tumor formation, development and deterioration Traditional treatments for most cancer cells tend to ignore a small number of cancer stem cells, Yang said Cancer stem cells have the ability of anti-tumor The recurrence of cancer after chemotherapy lies in the resistance of a few cancer stem cells The ideal treatment can not only induce the death of tumor cells, but also inhibit the self-renewal of tumor stem cells by regulating the function of oncogenic factors and tumor inhibitors At present, small RNA is a kind of endogenous genetic material that can effectively regulate tumor growth, and plays a role in regulating the function of tumor stem cells Yang Baihua's laboratory confirmed that Ganoderma lucidum spore oil can induce a variety of cancer cell death Its latest research shows that Ganoderma spore oil can also regulate the expression of miRNAs and selectively induce the death of tumor stem cells, but it has no effect on normal cells.