 Home > Active Ingredient News > Antitumor Therapy > Front Oncol: The efficacy of first-line and second-line treatment of advanced cholangiocarcinoma, and the effect of dose reduction on the efficacy

Front Oncol: The efficacy of first-line and second-line treatment of advanced cholangiocarcinoma, and the effect of dose reduction on the efficacy

 Last Update: 2021-12-04
 Source: Internet
 Author: User

Tags

single cell analysis

3 en 1

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

The prognosis of patients with unresectable cholangiocarcinoma is poor

This is a single-center retrospective study to screen the relevant data of patients with unresectable cholangiocarcinoma who received gemcitabine / platinum therapy from 2010 to 2018 .

The study included 58 patients, the median age at diagnosis was 59.

The median OS of the entire study population was 12.

Forty-one patients (71%) needed to reduce the intensity of the treatment plan

Twenty-one patients (36%) received 2L chemotherapy

There was no difference in specific survival rates between 2L chemotherapy regimens (p log-rank = 0.

Hematological toxicity is the most common AEs (69%)

In summary, studies have shown that gemcitabine /platinum therapy for advanced cholangiocarcinoma exhibits similar OS and PFS to randomized prospective phase II/III trials

Original source:

Möhring C, Feder J, Mohr RU, et al (2021) First Line and Second Line Chemotherapy in Advanced Cholangiocarcinoma and Impact of Dose Reduction of Chemotherapy: A Retrospective Analysis.

Möhring C, Feder J, Mohr RU, et al (2021) First Line and Second Line Chemotherapy in Advanced Cholangiocarcinoma and Impact of Dose Reduction of Chemotherapy: A Retrospective Analysis.
Front.
Oncol.
11:717397.
doi: 10.
3389/fonc.
2021.
717397 Möhring C, Feder J, Mohr RU, et al (2021) First Line and Second Line Chemotherapy in Advanced Cholangiocarcinoma and Impact of Dose Reduction of Chemotherapy: A Retrospective Analysis.
Front.
Oncol.
11:717397.
doi: 10.
3389/fonc.
2021.
717397

Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Crocetin27876-94-4

CAS No.: 27876-94-4

$1-1.1/G FOB

Betulinic acid472-15-1

CAS No.: 472-15-1

$1-1.1/G FOB

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 53-19-0

CAS No.: 53-19-0

Pharmacy Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.