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    Home > Active Ingredient News > Immunology News > Front Med: A Randomized Controlled Clinical Trial Study on the Treatment of Primary Sjogren’s Syndrome with Traditional Chinese Medicine

    Front Med: A Randomized Controlled Clinical Trial Study on the Treatment of Primary Sjogren’s Syndrome with Traditional Chinese Medicine

    • Last Update: 2021-11-02
    • Source: Internet
    • Author: User
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    Sjogren’s syndrome (SS) is achronic inflammatory autoimmune disease characterizedby dryness, fatigue and pain .
    At present, Western medicine has limited treatment of SS
    .


    To explore the efficacy and safety of traditional Chinese medicines in the treatment of primary SS, the Affiliated Hospital of Sun Yat-sen Medical University in Taichung, Taiwan conducted a 12-week randomized, double-blind, placebo-controlled clinical trial


    Sjogren’s syndrome Sjogren’s syndrome Sjogren, fatigue and pain Dryness, fatigue, and pain limited methods for the treatment of SS limited methods for the treatment of SS clinical trials clinical trials

    According to the classification criteria of the European and American Consensus Group (AECG), the study included 42 patients with SS, aged between 20 and 80, who were randomly divided into a traditional Chinese medicine treatment group and a placebo group (2:1)
    .


    Medicines: After breakfast served Gan Lu drink granules 6g, after dinner service Jiaweixiaoyaosan 6g, with Suanzaorentang 1 G, Caulis 1 g of


    Gan Lu Yin particles Gan Lu Yin particles Jiaweixiaoyaosan Jiaweixiaoyaosan Suanzaorentang 1 Suanzaorentang 1 Caulis Caulis patients reported index (ESSPRI) Sjogren's syndrome patients reported index (ESSPRI) Sjogren's syndrome

    42 patients were randomly divided into a traditional Chinese medicine treatment group with 28 cases and a control group with 14 cases
    .


    During the study period, there were 5 cases in the Chinese medicine group and 7 cases in the control group


    Although the ESSPRI score does not show the efficacy of traditional Chinese medicine in the treatment of Sjogren’s syndrome, there are other shortcomings, but the PSQI score shows that the formula can prolong the patient’s sleep time , and can also reduce the serum IgG level and the patient’s blood pressure
    .


    This provides a certain reference for clinical treatment of Sjogren's syndrome


    Extend the patient's sleep time.


    Literature source:

    Literature source:

    Chen HH, Lai JN, Yu MC, Chen CY, Hsieh YT, Hsu YF, Wei JC.


    Chen HH, Lai JN, Yu MC, Chen CY, Hsieh YT, Hsu YF, Wei JC.
    Traditional Chinese Medicine in Patients With Primary Sjogren's Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Front Med (Lausanne).
    2021 Sep 28;8:744194.
    doi: 10.
    3389/fmed.
    2021.
    744194.
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