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In summary, in most patients with severe SLE manifestations that do not respond to conventional immunosuppressive agents, a good therapeutic effect of the combination of BTZ and corticosteroids has been observed
Literature source: Walhelm T, Gunnarsson I, Heijke R, Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study.
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