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When talking about the product structure of DTP pharmacies, most people think of drugs for treating serious diseases, such as anti-tumor drugs, anti-rejection drugs after organ transplantation, immune biologics, drugs for rare diseases, etc.
Due to policy restrictions, it is a general trend that hospitals will not or rarely purchase supplementary drugs
.
In particular, some of the auxiliary drugs that have been used in hospitals for a long time and have been included in the state supervision in recent years, DTP pharmacy operators should pay attention to them when constructing the product structure
.
Adjuvant medication refers to drugs that help increase the effect of the main therapeutic drug or increase its efficacy by affecting the absorption, mechanism of action, and metabolism of the main therapeutic drug; or on the basis of the conventional treatment of the disease, it contributes to the disease or dysfunction Preventive and therapeutic drugs .
According to clinical application habits, auxiliary drugs generally include nutrition support drugs, prevent complications, conditioning Chinese patent medicines, etc.
, and are mainly used clinically for auxiliary treatment in the fields of anesthesia, tumors, surgery, liver diseases, cardiovascular and cerebrovascular diseases, diabetes, and infectious diseases.
.
Regarding the selection of auxiliary drugs, DTP pharmacies can combine the restrictions on the use of these drugs by the surrounding hospitals of the pharmacy and the clinical experience and habits of doctors in the hospital, and gradually introduce some products to form a relatively complete set that can provide clinical treatment for patients.
Combination of goods to help with medication .
In addition, to do something, you should also not do something .
Dosage form issues need to be paid attention to, preferably at room temperature, oral, cold chain, injection will increase the difficulty of patient medication .
Auxiliary medications in four layout points.
Auxiliary medications can be divided into 10 categories, including enhancing tissue metabolism, vitamins, electrolytes, enteral and parenteral nutrition, neurotrophic, free radical scavengers, immunomodulators, and promoting blood circulation and removing blood stasis.
Chinese medicine, liver disease adjuvant therapy, tumor adjuvant therapy medication .
The author believes that the following four types of supplementary medications are opportunities for DTP pharmacies .
1 Enteral and parenteral nutrition Enteral and parenteral nutritiondrugs are mainly used for clinical nutritional support for critically ill patients, and are generally used for patients with severe nutritional deficiency, severe trauma, and long-term failure to eat well .
Clinically, "undernutrition" is defined as the state of changes in subcellular, cellular and organ functions caused by dietary changes.
This state leads to an increased risk of morbidity and death in the human body, and this state can be achieved through adequate nutritional support.
Reversal
.
Inpatients with severe undereating for more than 7 days or a weight loss greater than 10% of their pre-morbid body weight can be considered as nutritional deficiency or high risk factors for developing malnutrition, and nutritional support treatment must be considered for these patients .
Standardized use can bring therapeutic aid value to patients with special drugs .
2 Immune-modulating auxiliary drugs: Immune auxiliary drugs refer to drugs that can increase, stimulate, activate, enhance or regulate the level of immune response of cellular immunity or humoral immunity .
Immunomodulators, also known as immune enhancing drugs or immune activating drugs, are drugs that can enhance the function of immune active cells or increase the phagocytic function of the mononuclear phagocyte system, thereby enhancing the immune function of the body .
Immune enhancing drugs can be divided into three categories according to their prerequisites: immune replacement drugs, immune restorative drugs and immune adjuvants .
The main indications include immunodeficiency, adjuvant therapy of malignant tumors and autoimmune diseases .
In recent years, a large number of immunomodulatory drugs have developed rapidly and are widely used in the clinical treatment of tumors.
They have a certain alleviating effect on tumors, can improve human immune function and improve the quality of life of patients .
3 Drugs for auxiliary treatment of liver disease Commonly used drugs for the treatment of liver disease can be divided into 9 categories: antiviral drugs, auxiliary drugs for protecting liver cells, immunomodulators, active ingredients of botanicals and traditional Chinese medicines, drugs for the treatment of cholestasis, and drugs for the prevention and treatment of hepatic encephalopathy , Antidote, anti-fibrosis and drugs for the treatment and prevention of portal hypertension and variceal bleeding .
Adjuvant drugs in liver diseases mainly have the effects of lowering enzymes, promoting detoxification, promoting energy metabolism, promoting protein synthesis, reducing jaundice, protecting liver cell membranes, improving microcirculation, regulating immunity, and anti-fibrosis.
These uses can reduce complications and adverse reactions, immune system, improve the quality of life and so on
.
The rational use of these drugs makes it more important for patients with liver disease to adapt to standard treatment drugs and even improve the efficacy .
4 Tumor Adjuvant Therapy Drugs Fujian Province has promulgated the "Guidelines for Clinical Use of Malignant Tumor Adjuvant Therapy in Fujian Province (Trial)".
The document defines the adjuvant treatment of malignant tumors as: malignant tumor patients undergoing surgery, radiation, chemotherapy and other treatments to prevent and treatment-related toxic side effects, and to improve resistance or related anti-tumor effect of having used a non-cytotoxic drugs, including medicine, an immune response regulating agents and the like .
As anti-tumor adjuvant drugs can reduce the adverse reactions of radiotherapy and chemotherapy, increase patient tolerance, improve patient quality of life, and promote the smooth progress of clinical chemotherapy regimens, they are more and more favored by doctors and patients .
Due to policy restrictions, it is a general trend that hospitals will not or rarely purchase supplementary drugs
.
In particular, some of the auxiliary drugs that have been used in hospitals for a long time and have been included in the state supervision in recent years, DTP pharmacy operators should pay attention to them when constructing the product structure
.
Adjuvant medication refers to drugs that help increase the effect of the main therapeutic drug or increase its efficacy by affecting the absorption, mechanism of action, and metabolism of the main therapeutic drug; or on the basis of the conventional treatment of the disease, it contributes to the disease or dysfunction Preventive and therapeutic drugs .
According to clinical application habits, auxiliary drugs generally include nutrition support drugs, prevent complications, conditioning Chinese patent medicines, etc.
, and are mainly used clinically for auxiliary treatment in the fields of anesthesia, tumors, surgery, liver diseases, cardiovascular and cerebrovascular diseases, diabetes, and infectious diseases.
.
Regarding the selection of auxiliary drugs, DTP pharmacies can combine the restrictions on the use of these drugs by the surrounding hospitals of the pharmacy and the clinical experience and habits of doctors in the hospital, and gradually introduce some products to form a relatively complete set that can provide clinical treatment for patients.
Combination of goods to help with medication .
In addition, to do something, you should also not do something .
Dosage form issues need to be paid attention to, preferably at room temperature, oral, cold chain, injection will increase the difficulty of patient medication .
Auxiliary medications in four layout points.
Auxiliary medications can be divided into 10 categories, including enhancing tissue metabolism, vitamins, electrolytes, enteral and parenteral nutrition, neurotrophic, free radical scavengers, immunomodulators, and promoting blood circulation and removing blood stasis.
Chinese medicine, liver disease adjuvant therapy, tumor adjuvant therapy medication .
The author believes that the following four types of supplementary medications are opportunities for DTP pharmacies .
1 Enteral and parenteral nutrition Enteral and parenteral nutritiondrugs are mainly used for clinical nutritional support for critically ill patients, and are generally used for patients with severe nutritional deficiency, severe trauma, and long-term failure to eat well .
Clinically, "undernutrition" is defined as the state of changes in subcellular, cellular and organ functions caused by dietary changes.
This state leads to an increased risk of morbidity and death in the human body, and this state can be achieved through adequate nutritional support.
Reversal
.
Inpatients with severe undereating for more than 7 days or a weight loss greater than 10% of their pre-morbid body weight can be considered as nutritional deficiency or high risk factors for developing malnutrition, and nutritional support treatment must be considered for these patients .
Standardized use can bring therapeutic aid value to patients with special drugs .
2 Immune-modulating auxiliary drugs: Immune auxiliary drugs refer to drugs that can increase, stimulate, activate, enhance or regulate the level of immune response of cellular immunity or humoral immunity .
Immunomodulators, also known as immune enhancing drugs or immune activating drugs, are drugs that can enhance the function of immune active cells or increase the phagocytic function of the mononuclear phagocyte system, thereby enhancing the immune function of the body .
Immune enhancing drugs can be divided into three categories according to their prerequisites: immune replacement drugs, immune restorative drugs and immune adjuvants .
The main indications include immunodeficiency, adjuvant therapy of malignant tumors and autoimmune diseases .
In recent years, a large number of immunomodulatory drugs have developed rapidly and are widely used in the clinical treatment of tumors.
They have a certain alleviating effect on tumors, can improve human immune function and improve the quality of life of patients .
3 Drugs for auxiliary treatment of liver disease Commonly used drugs for the treatment of liver disease can be divided into 9 categories: antiviral drugs, auxiliary drugs for protecting liver cells, immunomodulators, active ingredients of botanicals and traditional Chinese medicines, drugs for the treatment of cholestasis, and drugs for the prevention and treatment of hepatic encephalopathy , Antidote, anti-fibrosis and drugs for the treatment and prevention of portal hypertension and variceal bleeding .
Adjuvant drugs in liver diseases mainly have the effects of lowering enzymes, promoting detoxification, promoting energy metabolism, promoting protein synthesis, reducing jaundice, protecting liver cell membranes, improving microcirculation, regulating immunity, and anti-fibrosis.
These uses can reduce complications and adverse reactions, immune system, improve the quality of life and so on
.
The rational use of these drugs makes it more important for patients with liver disease to adapt to standard treatment drugs and even improve the efficacy .
4 Tumor Adjuvant Therapy Drugs Fujian Province has promulgated the "Guidelines for Clinical Use of Malignant Tumor Adjuvant Therapy in Fujian Province (Trial)".
The document defines the adjuvant treatment of malignant tumors as: malignant tumor patients undergoing surgery, radiation, chemotherapy and other treatments to prevent and treatment-related toxic side effects, and to improve resistance or related anti-tumor effect of having used a non-cytotoxic drugs, including medicine, an immune response regulating agents and the like .
As anti-tumor adjuvant drugs can reduce the adverse reactions of radiotherapy and chemotherapy, increase patient tolerance, improve patient quality of life, and promote the smooth progress of clinical chemotherapy regimens, they are more and more favored by doctors and patients .