 Home > Active Ingredient News > Antitumor Therapy > For this part of early breast cancer patients, adjuvant chemotherapy is useless!

For this part of early breast cancer patients, adjuvant chemotherapy is useless!

 Last Update: 2022-08-19
 Source: Internet
 Author: User

Tags

short

alh breast cancer

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Breast cancer (BC) is the most common malignancy in women and the leading cause of cancer-related death in women worldwid.

BC is a heterogeneous disease that responds markedly to treatment and consists of 4 distinct molecular subtype.

75,000 patients diagnosed with T1N0M0 BC were selected from the Surveillance, Epidemiology and End Results (SEER) databas.

With a median follow-up of 51 months, a total of 75139 patients with T1N0M0 BC were divided into three groups: T1a (n = 10073); T1b (n = 24951); and T1c (n = 40115.

In T1b BC, adjuvant chemotherapy was found to have significant effects on grade III and hormone receptor+ (HR+)/human epidermal growth factor receptor 2+ (HER2+), HR-/HER2+ and HR-/HER2- molecular subtypes, respectively influenc.

Adjuvant chemotherapy is beneficial for OS in grades II/III and T1c B.

We also obtained similar results in the external validation cohort, except that adjuvant chemotherapy produced differences in grade II and T1b BC in the external validation datase.

The study found that adjuvant chemotherapy is not beneficial and may even be harmful for patients with T1aN0M0 B.

Original source:

Shen K, Yao L, Zhu J, Gu X, Wang J, Qian W, Zheng Z, Fu D, Wu .

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Crocetin27876-94-4

CAS No.: 27876-94-4

$1-1.1/G FOB

Betulinic acid472-15-1

CAS No.: 472-15-1

$1-1.1/G FOB

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 53-19-0

CAS No.: 53-19-0

Pharmacy Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.