[follow the discussion] only by keeping in mind the original intention can Chinese pharmaceutical preparations develop healthily and comprehensively (I)

Abstract: pharmaceutics is one of the 573 second-class disciplines in the pharmaceutical discipline Due to the source or production site of APIs, the studied preparations include chemical preparations, traditional Chinese medicine preparations, biopharmaceutical preparations and hospital preparations With the development of pharmaceutics itself, it has developed from the first generation of common preparations to the fifth generation of computer-controlled biosensor response drug delivery preparations These problems studied by pharmaceutics Institute The problem belongs to the academic problem, but it is also an applied discipline, facing the objective and practical problems of public health medication and universal medical insurance These problems should be solved with scientific attitude and innovative spirit, and be alert to inadvertently slide into the quagmire of non science and ignoring innovation in advocating science and encouraging innovation Chinese pharmaceutical preparations need to develop in an all-round way! With more than 50 years of experience in the development process, reviewing the experience of science, learning and innovation, and inspired by President Xi's speech "keep in mind, keep moving forward", the author thinks about the positioning and core content of pharmaceutics, the diversity of dosage forms and the overall development of pharmaceutics, the key points of research and evaluation of pharmaceutics and the purpose or ultimate goal of research 。 It is realized that the pharmaceutical industry today can only develop healthily and comprehensively if it does not forget its original intention and looks forward, respects the objective laws of its own development and respects its own See you, chat with me! Key words: pharmaceutics, design of dosage forms, change of dosage forms, academic issues, I'm ashamed to have developed in an all-round way I've been involved in the pharmaceutical discipline for more than 50 years I've also participated in the revision of Pharmacopoeia and the drafting and revision of technical regulations for drug registration, but I haven't completed the registration application of a preparation completely as a person in charge I've also taught pharmaceutics in class, offered professional courses to postgraduates, and even organized the compilation of relevant monographs, which is called "writing books and making statements"; As the project leader, he has also carried out research on several NSFC projects, guided some graduate students, and thought he was doing knowledge and scientific research in Institutions of higher learning But what does pharmaceutics do, how should it be done, why, and how to do it better? Is the work done scientific, academic and innovative? Is it in line with the objective law of pharmaceutics development? I didn't fully understand before In recent years, inspired by Chairman Xi Jinping's 71 speech and his analysis of the article, he began to study the concepts and contents of science, academia and innovation superficially, and reviewed the development of pharmaceutics and its development again Here, I will exchange my experience, experience and thinking with you 1 Understanding of science, learning and innovation in the industry, scientificity, academic level and innovation have almost become the mantra and goal However, I understand that if I don't understand what is science, learning, innovation, and where my career comes from and why I go, it's difficult to control the direction of my career, stabilize my career path, and even create a sense of loss of fame 1 Scientific science is to make subjective knowledge conform to objective reality (the original appearance of objective things, including the law of real connection and change) And the practice of creating objective reality (things, conditions and environment) in line with subjective knowledge; the subjective knowledge in line with objective reality is scientific knowledge; the universal law in line with objective reality is scientific theory; the methods, measures and means of creating objective reality (to achieve the expected goal) in line with subjective knowledge are science and technology; the practice process of proving science is scientific research The practical activity of creating objective reality in accordance with subjective knowledge is the application of science; the real attribute in accordance with objective reality is scientificity From the connotation of science, I understand that there are two kinds of scientific activities, one is confirmatory and the other is creative; scientific research or application of science should have scientific knowledge, based on scientific theory, science and technology as means, and whether it is scientific or not as evaluation criteria Due to different occupations, different starting points and different goals may be adopted for scientific activities Is what you do scientific? Is it in line with objective reality? It is believed that whether science should be carried out in scientific practice, it is not necessary to repeat the existing scientific knowledge and scientific theory to do meaningless and useless work; "the problem of science should not be a little hypocritical and arrogant, but the opposite of it - honesty and humility." 2 Academic learning refers to systematic and specialized knowledge, which generally refers to higher education and research, and is the discipline of existence and its laws Academic thought is a more systematic proposition or idea formed by the understanding, understanding, practice, thinking, thinking, concentrated research, experience accumulation, induction and summary of the existence in the long-term specialized knowledge research Academic point of view is the understanding or opinion of individual academic issues in the study of expertise The academic thought can be formed by putting forward some related academic views on the same existence I understand that academic papers and monographs are usually not classified as advanced or backward, but as reference Whether there is authority or not mainly depends on whether the discussion is reasonable or unreasonable, whether there is something or nothing, whether the writing is rigorous or flower tip, whether the practice is implemented or boasted, whether it is fruitful or on paper 3 Innovation and innovation refers to updating, changing and creating new things Innovation is a kind of behavior which is guided by the existing thinking mode and puts forward different opinions from the conventional or ordinary people's thinking It uses the existing knowledge and materials to update, improve or create new things, methods, elements, paths and environments in a specific environment in line with the idealized needs or to meet the social needs, and can obtain certain beneficial effects I understand that innovation belongs to the emancipation of the mind, not to be conformed to, forge ahead with determination and dare to explore; but as long as you are not satisfied with the status quo, have independent pursuit, have a sense of career responsibility, and innovation is not out of reach, update, change and creation have been with you at any time Reflecting on the past, is the subjective understanding of science, learning and innovation in line with the objective reality of the work? For a time, he was more than awed, and regarded academic and scientific achievements as unfathomable He regarded books as the golden rule, the words of books as the purport, and he could not go beyond the thunder pool He regarded innovation as invention and creation, which was unfathomable, and ordinary people were not willing to ask Such a state of mind, to the lack of innovative spirit, how to talk about creating courage, craftsman spirit? Once again, it was lack of awe, impetuosity and following the trend, lack of independence and self-confidence, greedy for perfection, and forgetting where they came from and why they left What's the matter! In fact, as far as the connotation of science and innovation is concerned, everyone is carrying out the practical activities of updating, changing and creating to make their subjective knowledge conform to the objective reality every day The scientific development concept put forward by the previous government does not prove that scientific activities can be participated by everyone! It can be seen that science and innovation can not be mystified, nor can we distinguish the noble from the humble, comment on the level of high and low, and judge the value orientation As long as we revise our behavior at any time to make it conform to the changing objective reality, it will be scientific and innovative Today's advocacy of mass entrepreneurship and innovation is an excellent interpretation of innovation! However, we should still respect science, learning and innovation, respect their own objective laws of development, and fear the consequences of violating them Different scientific activities should not be evaluated on the basis of their level, advancement and backwardness In the same scientific activity, they are the first to make the subjective knowledge conform to the objective reality, put forward distinct academic views or ideas and recognized by the industry They are often praised for their high academic level and evaluated as having extremely high academic value In scientific activities, the scientific methods, means and conditions applied follow the discipline The development of science and technology is indeed advanced and backward Pharmaceutics as a discipline, for decades, in the practice, induction and summary of the predecessors who "entered" the discipline, the academic thought has become a system Subsequently, with the development of related science and technology, the continuous practice of pharmaceutical workers has become increasingly rich and perfect In the academic circle, academic thoughts and opinions can only be exchanged equally and discussed together Whether they can be recognized is not determined by the person who put forward them, but by whether they have reference and reference value Of course, they also need to continue to practice, advocate and spread, and finally let time test them To be continued.. Retired, should have been a quiet spectator, but from time to time alarmist Funny! Only because I was in the beginning of the potion, so that I could continue to speak for the potion Wish! Indifference to utility is the result of occupation; when discussing medicine, the original intention is not lost Yaxinghu! Leisure time, reverie; enjoy yourself, aftertaste For small talk! Hou Shixiang, retired professor, Huaxi pharmaceutical college, Sichuan University