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Incyte announced today that the U.
GVHD is a potentially fatal complication that may occur after allogeneic stem cell transplantation.
Rucotinib is an oral "first-in-class" JAK1/JAK2 inhibitor.
This application is based on the results of the Phase 3 clinical trial REACH3 in patients with steroid refractory chronic GVHD.
In addition, rucotinib has reached a number of key secondary endpoints of the trial, including the median failure-free survival of rucotinib at week 24, which is significantly longer than the best existing treatment.
"Chronic GVHD is a life-threatening complication after stem cell transplantation, which brings a burden to the fragile patient population, which now has limited treatment options," said Dr.
Note: This article is intended to introduce medical and health research, not to recommend treatment options.
Reference materials:
[1] Incyte Announces Acceptance and Priority Review of sNDA for Jakafi® (ruxolitinib) as a Treatment for Patients with Chronic Graft-Versus-Host Disease.