FDA approves Zemdri (plazomicin) for treatment of complex urinary tract infections
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Last Update: 2020-06-11
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Source: Internet
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Author: User
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recently, Achaogen(announcing that the U.SFDA(approved for its Zemdri (plazomicin) for patients with complex urinary tract infections (cUTI) caused by certain Ecoli infections, including those with pynoreneutic nephritisabout Zemdri
Zemdri is an intravenousdrug(administered once a day)It is worth mentioning that this approval makes Zemdri the only daily treatment for cUTIZemdri is designed to be an antibiotic that can be used against aminoglycoside modifiers, the most common aminoglycoside resistance mechanism in the EcoliZemdri is a new generation of aminoglycoside antibiotics with anti-specific Ecoli activity, including CRE (carbon ilostenin antibiotic resistance) and Ecoli (ultra-broad spectrum beta-lactamase) producedFDA approval is based on Zemdri's EPIC ClinicalTrial ( The experimental results showthat that Zemdri successfully achieved the main therapeutic end of non-performance compared with meropenem Compared to Meropinan, patients treated with Zemdri had a significant overall cure rate (81.7% VS 70.1%) and the elimination of the proportion of infected microorganisms The FDA-approved antibiotic folds at 2 mcg / mL, i.e greater than 99% e coli, C.B.A And Gyeloba are sensitive to Zemdri at the data point in addition , Zemdri has shown good tolerance and safety
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