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▎Edited by WuXi AppTec Content Team
TG Therapeutics recently announced that its investigational antibody ublituximab targeting the CD20 protein has achieved the primary endpoint in the ULTIMATE I & II Phase 3 clinical trial in the treatment of relapsing multiple sclerosis (RMS) patients.RMS is a chronic central nervous system demyelinating disease caused by the immune system attacking the myelin sheath that protects nerves, and includes relapsing-remitting multiple sclerosis (RRMS) as well as secondary progressive multiple sclerosis (SPMS)
Image source: 123RF
ULTIMATE I and ULTIMATE II are two independent, randomized, double-blind, active-controlled, global, multicenter Phase 3 clinical trials to examine the efficacy, safety and efficacy of ublituximab compared with the common MS oral drug teriflunomide in patients with RMS.
▲Mr.
Michael S.