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Express develops breakthrough covalent drugs, Xinrui completes $75 million in Series A financing

 Last Update: 2022-08-12
 Source: Internet
 Author: User

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Today, Terremoto Biosciences announced the completion of a $75 million Series A financi.

Advances its covalent platform targeting lysine (Lys)

Historically, covalent drugs worked by forming covalent bonds with cysteines (Cys) on the surface of protei.

Cysteine is uncommon in proteins, thus limiting the number of targets that can be targeted by this mechanism

Terremoto's technology platform aims to expand the types of amino acids that covalent drugs can bind to and develop covalent drugs that target lysine bindi.

Lysines are widely distributed in the proteome and are present in the drug-action "pockets" of most protei.

"At Terremoto, we are leveraging covalent chemistry to develop more specific, potent, and superior small-molecule drugs for a range of highly complex and serious diseases," said .

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