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A few days ago, Sanofi announced that it has reached an agreement to acquire Amunix Pharmaceuticals
The acquisition will expand Sanofi's T-cell conjugator (TCE) and cytokine therapy pipeline
The protease release stealth Pro-XTEN (Protease-Releasable Masking Technology) technology platform developed by Amunix utilizes the inherent high protease activity in the tumor microenvironment to preferentially activate drugs, thereby reducing toxicity without affecting normal tissues
Take advantage of the inherent high protease activity in the tumor microenvironment to preferentially activate drugs, thereby reducing toxicity without affecting normal tissues
▲Pro-XTEN-XPAT-XPAC technology platform composition principle (picture source: Amunix company official website)
▲Pro-XTEN-XPAT-XPAC technology platform composition principle (picture source: Amunix company official website)Amunix has further developed a new bispecific XPAT platform by using the clinically proven XTEN technology, which can deliver bispecific antibodies to patients in lower doses, thereby reducing toxic side effects
It can deliver bispecific antibodies to patients in lower doses, thereby reducing toxic side effects
▲XPAT technology platform (picture source: Amunix company official website)
▲XPAT technology platform (picture source: Amunix company official website)Dr.
The Amunix technology platform uses the next generation of smart biological product methods to achieve precise customized delivery of drugs