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Express delivery of more than half of patients with ulcerative colitis that has been relieved for nearly 3 years, and Janssen IL-12/23 inhibitor has a positive long-term effect

 Last Update: 2021-08-09
 Source: Internet
 Author: User

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A few days ago, Johnson & Johnson's Janssen company (Janssen) announced its IL-12/IL-23 inhibitor Stelara (ustekinumab) for the treatment of moderate to severe active ulcerative colitis (UC) patients with long-term extended research data
.

The data showed that more than half (55.

Ustekinumab developed by Janssen is a humanized IL-12 and IL-23 antibody
.

IL-12 and IL-23 are important cytokines that regulate the immune system and immune-mediated inflammatory diseases in the human body

"Despite substantial progress in recent years, many UC patients are still struggling to seek sustained relief of symptoms, especially treatments that do not require steroids
.

" said Dr.
Bruce E.

Reference materials:

[1] STELARA® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Rates in Adults with Moderately to Severely Active Ulcerative Colitis at Nearly Three Years in Long-Term Extension of Phase 3 Trial.

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