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    Home > Active Ingredient News > Antitumor Therapy > Express $700 million to help develop anti-cancer bispecific nanoantibodies! Seagen reached a partnership

    Express $700 million to help develop anti-cancer bispecific nanoantibodies! Seagen reached a partnership

    • Last Update: 2022-10-01
    • Source: Internet
    • Author: User
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    ▎Editor of WuXi AppTec content team

    Seagen today announced an exclusive licensing agreement with LAVA Therapeutics, which will jointly develop, manufacture and commercialize the in-development bispecific VHH LAVA-1223




    LAVA's proprietary Gammabody platform is a technology for the development of spot-based bispecific nanoantibodies targeting Vγ9Vδ2 T cells and tumor-associated antigens



    ▲Gammabody platform (Image source: LAVA official website)


    LAVA-1223, developed through the Gammabody platform, can specifically target solid tumors expressing EGFR and activate Vγ9Vδ2 T cells



    Under this agreement, Seagen will be granted the exclusive global license of LAVA-1223 and will pay an advance payment of $50 million from LAVA, with a total of up to $650 million based on developmental, regulatory and commercial milestones



    "Seagen is committed to fostering innovative therapies to improve the lives of





    WuXi AppTec provides integrated, end-to-end new drug development and manufacturing services to the global biopharmaceutical industry, covering the fields


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