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At present, neoadjuvant chemotherapy (NAC) has been widely used in the treatment of
breast cancer .
Neoadjuvant chemotherapy is commonly used in patients with locally advanced and inflammatory breast cancer to reduce tumor staging for breast-conserving surgery
At present, neoadjuvant chemotherapy (NAC) has been widely used in the treatment of breast cancer .
Neoadjuvant chemotherapy is commonly used in patients with locally advanced and inflammatory breast cancer to reduce tumor staging for breast-conserving surgery .
Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) is the best imaging technique for evaluating response and predicting pathological response after neoadjuvant therapy in breast cancer, with an accuracy rate of approximately 91%
Recently, a study published in the journal European Radiology evaluated the role of DWI in predicting DWI after one cycle of NAC through two-dimensional (2D) ROI-ADC measurements and three-dimensional (WL) whole-lesion (WL) segmentation of ADC histograms.
Role in breast cancer pathology and radiological response .
Between January 2016 and December 2019, 55 female patients were enrolled in this prospective, single-center study
Of the 48 patients, 9 achieved pCR
Fig.
Receiver operating characteristic (ROC) curves predicted by variant MRI parameters .
a RECIST response .
b Pathological complete response (pCR) of surgical specimen .
Receiver operating characteristic (ROC) curves predicted by variant MRI parameters .
a RECIST response .
b Pathological complete response (pCR) of surgical specimen .
The results of this study demonstrate that the marked increase of ROI-ADC in breast tumors under DWI can predict the complete pathological and imaging response after one cycle of NAC
ADC histogram analysis
Original source :
Nathalie A Hottat , Dominique A Badr , Sophie Lecomte ,et al .
Value of diffusion-weighted MRI in predicting early response to neoadjuvant chemotherapy of breast cancer: comparison between ROI-ADC and whole-lesion-ADC measurements .
Nathalie A Hottat Dominique A Badr Sophie Lecomte ,et al Value of diffusion-weighted MRI in predicting early response to neoadjuvant chemotherapy of breast cancer: comparison between ROI-ADC and whole-lesion-ADC measurements 10.
1007/s00330-021-08462-z 10.
1007 /s00330-021-08462-z Leave a message here
