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European Radiology: The value of DTI in the differential diagnosis of neuromyelitis optica spectrum disorders and multiple sclerosis

 Last Update: 2022-09-06
 Source: Internet
 Author: User

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Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) are two major inflammatory demyelinating diseases of the central nervous system, with similar clinical symptoms and imaging findings, but widely differing treatment modalities

Conventional magnetic resonance imaging (cMRI) is often used to qualitatively assess the morphology of the entire visual pathway and visual cortex

A study published in the European Radiology journal used FA to assess optic nerve damage in NMOSD and MS, compared the differences in the pattern of optic nerve involvement between the two, and explored the feasibility of using FA to differentiate the two diseases

Thirty-one NMOSD patients, 25 MS patients, and 17 healthy controls (HC) were included in this study, each of whom underwent optic nerve DTI

The FA value of the entire optic nerve, especially the posterior segment of the optic nerve, was significantly decreased in type VI NMOSD (P<0.

The present study found that NMOSD-ON and MS-ON resulted in decreased FA values in different segments of the optic nerve

Original source:

Yan Xie,Yan Zhang,Yihao Yao,et al.

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