European Radiology: Association between infarct core predicted by CT perfusion and clinical outcomes of acute stroke

Assessment of inactive tissue in the infarcted area or infarct core is one of the most important baseline imaging markers for assessing the condition of acute stroke patients .

Assessment of inactive tissue or infarct core in the infarct zone is one of the most important baseline imaging markers for assessing stroke status in acute stroke patients .

Due to the high clinical availability of CTP , this technique is widely used in acute stroke to obtain predicted infarct core (pIC) volume .

Recently, a study published in the European Radiolog y , under the assumption that the prognostic accuracy of pIC can be modified by some baseline and treatment-related variables, in an acute ischemic stroke with occluded vessels in the large anterior circulation In the patient cohort , CTP imaging was performed in all patients within 8 hours of stroke to identify the most relevant modifiers between pIC and clinical outcome .

This study included 828 patients with acute proximal carotid occlusion who underwent whole-brain CTP imaging within 8 hours of stroke onset .

The volume of pIC was significantly associated with poor clinical outcome (OR = 2.

This study suggests that CTP - derived pICs have limited accuracy in predicting clinical outcomes in selected subgroups of patients with acute ischemic stroke that were imaged within 8 hours of stroke and defined by specific baseline or treatment variables .

Original source :

Carlos Laredo , Aleix Solanes , Arturo Renú , et al .

Carlos Laredo Aleix Solanes Arturo Renú ,et al Clinical and therapeutic variables may influence the association between infarct core predicted by CT perfusion and clinical outcome in acute stroke Clinical and therapeutic variables may influence the association between infarct core predicted by CT perfusion and clinical outcome in acute stroke 10.
1007/s00330-022-08590-0 10.
1007/s00330-022-08590-0

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