 Home > Active Ingredient News > Antitumor Therapy > Eur Radiol: What is the impact of low-grade glioma DNA copy number subtypes on the prognosis?

Eur Radiol: What is the impact of low-grade glioma DNA copy number subtypes on the prognosis?

 Last Update: 2021-03-20
 Source: Internet
 Author: User

Tags

rotational development program

7.4 ph water

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

The incidence of central nervous system malignant tumors is getting higher and higher, and the 5-year relative survival rate is only 35.

diagnosis

DNA copy number variation (CNV) is a quantitative structural rearrangement, including duplication, deletion, and high-order amplification.

The CN2 subtype is associated with the shortest overall survival (OS).

Recently, a study published in the journal European Radiology used MR-based preoperative nomograms to predict the DNA copy number subtypes of LGG patients (CN1-CN3), demonstrating the MR characteristics of low-grade gliomas and the DNA copy number Type of relationship.

The overall survival (OS) data of the patients were analyzed.

The CN2 subtype was associated with the shortest median OS (CN2 subtype vs.

Figure 1 Correlation matrix between MR qualitative characteristics and DNA copy number subtypes

Figure 2 (a) No bleeding, unclear edges, no extranodular growth, and volume ≥60 cm ^{3 are} related to CN1 subtypes.

Patients with CN2 subtype have the shortest OS.

Original source:

Siwei Zhang,Shanshan Wu,Yun Wan,et al.

Siwei Zhang,Shanshan Wu,Yun Wan,et al.
Development of MR-based preoperative nomograms predicting DNA copy number subtype in lower grade gliomas with prognostic implication.
DOI: org/10.
1007/s00330-020-07350-2">10.
1007/s00330-020-07350-2org/10.
1007/s00330-020-07350-2"> 10.
1007/s00330-020-07350 -2 Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Crocetin27876-94-4

CAS No.: 27876-94-4

$1-1.1/G FOB

Betulinic acid472-15-1

CAS No.: 472-15-1

$1-1.1/G FOB

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 53-19-0

CAS No.: 53-19-0

Pharmacy Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.