Eur Radiol: Calcification of Mammary Targets - What is the clinical significance of suspected morphological calcification?

A variety of suspicious forms of calcification stoves are often found in mammary targets, which can be used to detect the presence of breast cancer and predict its invasiveness.
The American Radiological Society's Breast Imaging Reporting and Data System (ACR BI-RADS) defines "suspicious calcification" as anaemic, coarsely heterogeneous, fine polygonal, and thin-line or branched.
currently, ACR BI-RADS recommends using distributions to describe suspicious calcification stoves.
studies have shown that positive predictive value (PPVs) when the distribution is included in the calcification assessment is significant and will affect the further classification of calcification stoves.
A recent study published in the journal European Radiology included distribution and clinical factors in two separate female cohorts, evaluating PPV with suspicious forms of calcification and providing more practical guidance for the treatment of suspected calcification stoves detected in mammary targets.
This retrospective study included 1076 consecutive female patients from two queues (queue A, 556; queue B, 520) who observed suspicious forms of calcification lesions in mammography, each of which was pathologically confirmed or followed by a target film.
using generalized estimation equations to analyze and compare the average calcified PPV of readers through logistic regression.
multi-factor logistic regression analysis to assess independent factors associated with PPV for suspected calcification.
16.8 per cent and 15.2 per cent, respectively, for readers of queues A and B.
average PPV by pattern in queues A and B was as follows: 9.1% and 6.4% adversity, 16.1% and 22.1% crude heterogeneity, respectively; Fine polygonality of 78.8 per cent and 44.7 per cent; 78.6% and 85.1% of thin lines or branches (p .lt;0.001).
2.6 per cent and 2.6 per cent, respectively, and the regional astration calcification stoves were 3.6 per cent and 3.1 per cent, respectively.
in diffuse astration calcification, the PPV ranged from 0.0 to 1.9 percent for women aged ≥50 and women without a personal history of breast cancer.
Comparing the average PPV of readers with other suspected calcification lesions in the two queues, the average PPV of readers of a fixed calcification stove was lower than that of other suspected forms of calcified cooker, and belonged to BI-RADS 4a assessment (PPV 2-10%).
average PPV of less than 2.0% was detected in women over 50 years of age who did not have a personal history of breast cancer.
further prospective studies are needed to determine whether these patients' treatment requires imaging follow-up.