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Eur J Cancer: Efficacy and safety of gemcitabine + albumin-bound paclitaxel versus FOLFIRINOX as first-line treatment of advanced pancreatic cancer

 Last Update: 2021-05-20
 Source: Internet
 Author: User

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Pancreatic cancer is a common malignant tumor with a high degree of malignancy.

This study aims to compare the efficacy and safety of gemcitabine + albumin-bound paclitaxel (GN) versus FOLFIRINOX as the first-line treatment of advanced pancreatic cancer.

The study included 455 patients with advanced pancreatic cancer, including 297 (65.

Unadjusted analysis, median PFS: GN vs FOLFIRINOX was 4.

The analysis of treatment-related adverse events was also comparable in the two groups.

In summary, gemcitabine + albumin-bound paclitaxel is comparable to FOLFIRINOX first-line treatment of advanced pancreatic cancer.

Original source:

ncbi.

ncbi.
nlm.
nih.
gov/?term=Riedl+JM&cauthor_id=33951545">Jakob M Riedl, ncbi.
nlm.
nih.
gov/?term=Posch+F&cauthor_id=33951545">Florian Posch , ncbi.
nlm.
nih.
gov/?term=Horvath+L&cauthor_id=33951545">Lena Horvath , et al.
Gemcitabine/nab-Paclitaxel versus FOLFIRINOX for palliative fifirst-line treatment of advanced pancreatic cancer: A propensity score analysis.
Eur J Cancer.
2021 May 2;151:3-13.
DOI: 10.
1016 / j.
ejca.
2021.
03.
040 Online Ahead of Print.
.
ncbi.
nlm.
nih.
gov/?term=Riedl+JM&cauthor_id=33951545">Jakob M Riedl ncbi.
nlm.
nih.
gov/?term=Posch+F&cauthor_id=33951545">Florian Posch ncbi.
nlm.
nih.
gov/?term=Horvath+L&cauthor_id=33951545">Lena Horvath's

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