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Eur Heart J: The causal relationship between the length of sleep and 12 cardiovascular diseases

 Last Update: 2021-04-13
 Source: Internet
 Author: User

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Observational studies suggest that sleep time and a lot of medsci.

medsci.

Recently, Eur Heart J, an authoritative journal in the cardiovascular field, published a research article.

The researchers analyzed 404044 participants in the UK biobank and assessed the causal relationship between 12 cardiovascular diseases and genetic variants associated with continuous, short (≤6 hours) and long (≥9 hours) sleep time.

Linear MR analysis showed that after multiple corrections, the genetically predicted sleep time was negatively correlated with hypertension, atrial fibrillation, pulmonary embolism and chronic ischemic heart disease (P<0.

Myocardial infarction

This study shows that genetically predicted short sleep time is a potential risk factor for several cardiovascular diseases, while genetically predicted long sleep time is unlikely to be a causal risk factor for cardiovascular disease.

Genetically predicted short sleep time is a potential risk factor for several cardiovascular diseases, while genetically predicted long sleep time is unlikely to be a causal risk factor for cardiovascular disease.

Original source:

Sizhi Ai,et al.

org/10.
1093/eurheartj/ehab170" target="_blank" rel="noopener">Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank

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