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EU approves bispecific antibody Tecvayli (teclistamab) for the treatment of adults with relapsed/refractory multiple myeloma (RRMM)

 Last Update: 2022-09-24
 Source: Internet
 Author: User

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Janssen announced today that the European Commission (EC) has approved the conditional marketing of Tecvayli (teclistamab), a bispecific antibody targeting B cell maturation antigen (BCMA), for the treatment of adults with relapsed/refractory multiple myeloma (RRMM).

This approval of teclistamab is based on results from the Phase 1/2 MajesTEC-1 trials (NCT03145181 and NCT04557098) in which patients with relapsed/refractory disease received teclistamab at 1.

Multiple myeloma is the second most common hematological malignancy, accounting for about 10% of hematological malignancies

BCMA is a popular target for the treatment of B-cell blood cancers

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