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Boehringer Ingelheim (Boehringer Ingelheim) and Eli Lilly and Company (Eli Lilly and Company) today announced that the US FDA has granted Empagliflozin (English trade name Jardiance) breakthrough therapy designation for the treatment of heart failure with preserved ejection fraction (HFpEF) Adult patients
The decision is based on the results of the landmark phase 3 clinical trial EMPEROR-Preserved.
Heart failure is a progressive, debilitating and potentially fatal disease that occurs when the heart cannot provide enough circulation to meet the body's demand for oxygenated blood
Empagliflozin is a highly selective sodium-glucose cotransporter 2 (SGLT2) inhibitor that is taken orally once a day.
Reference materials:
[1] FDA grants Jardiance® Breakthrough Therapy designation for heart failure with preserved ejection fraction.
(The original text has been deleted)