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Eli Lilly's CDK4/6 inhibitor receives FDA approval for the first time to treat early-stage breast cancer

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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Today, Eli Lilly (Eli Lilly and Company) announced that the US FDA has approved the CDK4/6 inhibitor Verzenio (abemaciclib) for extended indications, combined with endocrine therapy (tamoxifen or aromatase inhibitors), and adjuvant treatment of hormone receptors.

Breast cancer has surpassed lung cancer as the most common cancer in the world, with approximately 2.

This approval is based on an open-label, phase 3 clinical trial of patient subgroup analysis results

The analysis of this patient subgroup showed that Verzenio combined with endocrine therapy reduced the risk of relapse by approximately 36% compared with endocrine therapy alone (HR=0.

Verzenio (abemaciclib) is a CDK4/6 inhibitor

Reference materials:

[1] FDA Approves Verzenio® (abemaciclib) as the First and Only CDK4/6 Inhibitor for Certain People with HR+ HER2- High Risk Early Breast Cancer.

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