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At present, antitumor drugs are classified according to their drug sources and mechanism of action, which is of practical significance for grasping the characteristics of drugs and designing combined drug regimens
At present, antitumor drugs are classified according to their drug sources and mechanism of action, which is of practical significance for grasping the characteristics of drugs and designing combined drug regimens
1.
1.
In recent years, the progress of cytotoxic drugs is limited.
In recent years, the progress of cytotoxic drugs is limited.
2.
2.
Currently commonly used targeted drugs include anti-EGFR, ALK, MET and other inhibitors, as well as multi-target multi-kinase inhibitors
Currently commonly used targeted drugs include anti-EGFR, ALK, MET and other inhibitors, as well as multi-target multi-kinase inhibitors
3.
3.
Monoclonal antibodies are antibodies directed against a specific epitope and also have a targeting effect
Monoclonal antibodies are antibodies directed against a specific epitope and also have a targeting effect
4.
4.
In tumor immunotherapy, immune checkpoint inhibitors are the most in-depth and extensive research, which is the second time to change the tumor treatment landscape after targeted therapy
.
In addition to the common inhibition of PD-1, PD-L1, and CTLA-4, research on dual-antibody drugs is also underway
.
.
In addition to the common inhibition of PD-1, PD-L1, and CTLA-4, research on dual-antibody drugs is also underway
.
5.
Hormones
Hormones 5.
Hormones
Hormonal drugs are a common treatment component for sex hormone-affected tumors such as breast and prostate cancer
.
Commonly used hormonal drugs are summarized in the table below
.
.
Commonly used hormonal drugs are summarized in the table below
.
6.
Antibody-conjugated drugs
Antibody Conjugates 6.
Antibody Conjugates
Antibody-Drug Conjugate (ADC) is another hot spot in current drug research
.
ADCs couple cytotoxic drugs to monoclonal antibodies through linkers.
Using the characteristics of antigen-antibody specific binding, the cytotoxic drugs can be specifically delivered to the tumor to play a killing effect
.
A number of ADCs are already on the market
.
In addition, drugs targeting targets such as Trop2 and CD79 are also in clinical trials
.
.
ADCs couple cytotoxic drugs to monoclonal antibodies through linkers.
Using the characteristics of antigen-antibody specific binding, the cytotoxic drugs can be specifically delivered to the tumor to play a killing effect
.
A number of ADCs are already on the market
.
In addition, drugs targeting targets such as Trop2 and CD79 are also in clinical trials
.
7.
Other
In addition, drugs that are difficult to be classified, such as biological response modifiers, differentiation inducers, and tumor vaccines, are included in other categories
.
.
8.
Auxiliary drugs
Auxiliary drugs 8.
Auxiliary drugs
Tumor adjuvant drugs are also an important part of anti-tumor therapy, helping to reduce adverse events of anti-tumor therapy and relieve symptoms of patients
.
.
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